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Transcriptomic Analysis of Human Astrocytes In Vitro Reveals Hypoxia-Induced Mitochondrial Dysfunction, Modulation of Metabolism, and Dysregulation of the Immune Response.
Int J Mol Sci. 2020 Oct 28;21(21):8028. doi: 10.3390/ijms21218028.
Int J Mol Sci. 2020.
PMID: 33126586
Free PMC article.
C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis.
Allen SP, Hall B, Woof R, Francis L, Gatto N, Shaw AC, Myszczynska M, Hemingway J, Coldicott I, Willcock A, Job L, Hughes RM, Boschian C, Bayatti N, Heath PR, Bandmann O, Mortiboys H, Ferraiuolo L, Shaw PJ.
Allen SP, et al.
Brain. 2019 Dec 1;142(12):3771-3790. doi: 10.1093/brain/awz302.
Brain. 2019.
PMID: 31647549
Free PMC article.
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Lipid metabolism in astrocytic structure and function.
Lee JA, Hall B, Allsop J, Alqarni R, Allen SP.
Lee JA, et al.
Semin Cell Dev Biol. 2021 Apr;112:123-136. doi: 10.1016/j.semcdb.2020.07.017. Epub 2020 Aug 6.
Semin Cell Dev Biol. 2021.
PMID: 32773177
Review.
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Adenosine deaminase, not immune to a mechanistic rethink in central nervous system disorders?
Hall B, George JG, Allen SP.
Hall B, et al.
Histol Histopathol. 2022 Mar;37(3):189-212. doi: 10.14670/HH-18-404. Epub 2021 Dec 9.
Histol Histopathol. 2022.
PMID: 34881804
Free article.
Review.
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Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis.
Allen SP, Hall B, Castelli LM, Francis L, Woof R, Siskos AP, Kouloura E, Gray E, Thompson AG, Talbot K, Higginbottom A, Myszczynska M, Allen CF, Stopford MJ, Hemingway J, Bauer CS, Webster CP, De Vos KJ, Turner MR, Keun HC, Hautbergue GM, Ferraiuolo L, Shaw PJ.
Allen SP, et al.
Brain. 2019 Mar 1;142(3):586-605. doi: 10.1093/brain/awy353.
Brain. 2019.
PMID: 30698736
Free PMC article.
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Amyotrophic lateral sclerosis alters the metabolic aging profile in patient derived fibroblasts.
Gerou M, Hall B, Woof R, Allsop J, Kolb SJ, Meyer K, Shaw PJ, Allen SP.
Gerou M, et al.
Neurobiol Aging. 2021 Sep;105:64-77. doi: 10.1016/j.neurobiolaging.2021.04.013. Epub 2021 Apr 27.
Neurobiol Aging. 2021.
PMID: 34044197
Free PMC article.
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Unbiased metabolome screen leads to personalized medicine strategy for amyotrophic lateral sclerosis.
Boddy S, Islam M, Moll T, Kurz J, Burrows D, McGown A, Bhargava A, Julian TH, Harvey C, Marshall JN, Hall BP, Allen SP, Kenna KP, Sanderson E, Zhang S, Ramesh T, Snyder MP, Shaw PJ, McDermott C, Cooper-Knock J.
Boddy S, et al.
Brain Commun. 2022 Mar 17;4(2):fcac069. doi: 10.1093/braincomms/fcac069. eCollection 2022.
Brain Commun. 2022.
PMID: 35441136
Free PMC article.
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