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S[+] Apomorphine is a CNS penetrating activator of the Nrf2-ARE pathway with activity in mouse and patient fibroblast models of amyotrophic lateral sclerosis.
Mead RJ, Higginbottom A, Allen SP, Kirby J, Bennett E, Barber SC, Heath PR, Coluccia A, Patel N, Gardner I, Brancale A, Grierson AJ, Shaw PJ. Mead RJ, et al. Among authors: allen sp. Free Radic Biol Med. 2013 Aug;61:438-52. doi: 10.1016/j.freeradbiomed.2013.04.018. Epub 2013 Apr 19. Free Radic Biol Med. 2013. PMID: 23608463 Free PMC article.
Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism, hypoxia-response and RNA processing functions.
Raman R, Allen SP, Goodall EF, Kramer S, Ponger LL, Heath PR, Milo M, Hollinger HC, Walsh T, Highley JR, Olpin S, McDermott CJ, Shaw PJ, Kirby J. Raman R, et al. Among authors: allen sp. Neuropathol Appl Neurobiol. 2015 Feb;41(2):201-26. doi: 10.1111/nan.12147. Neuropathol Appl Neurobiol. 2015. PMID: 24750211 Free PMC article.
Astrocyte adenosine deaminase loss increases motor neuron toxicity in amyotrophic lateral sclerosis.
Allen SP, Hall B, Castelli LM, Francis L, Woof R, Siskos AP, Kouloura E, Gray E, Thompson AG, Talbot K, Higginbottom A, Myszczynska M, Allen CF, Stopford MJ, Hemingway J, Bauer CS, Webster CP, De Vos KJ, Turner MR, Keun HC, Hautbergue GM, Ferraiuolo L, Shaw PJ. Allen SP, et al. Among authors: allen cf. Brain. 2019 Mar 1;142(3):586-605. doi: 10.1093/brain/awy353. Brain. 2019. PMID: 30698736 Free PMC article.
Lipid metabolism in astrocytic structure and function.
Lee JA, Hall B, Allsop J, Alqarni R, Allen SP. Lee JA, et al. Among authors: allen sp. Semin Cell Dev Biol. 2021 Apr;112:123-136. doi: 10.1016/j.semcdb.2020.07.017. Epub 2020 Aug 6. Semin Cell Dev Biol. 2021. PMID: 32773177 Review.
Peripheral Glycolysis in Neurodegenerative Diseases.
Bell SM, Burgess T, Lee J, Blackburn DJ, Allen SP, Mortiboys H. Bell SM, et al. Among authors: allen sp. Int J Mol Sci. 2020 Nov 24;21(23):8924. doi: 10.3390/ijms21238924. Int J Mol Sci. 2020. PMID: 33255513 Free PMC article. Review.
88 results