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Apoptosis oxidative damage-mediated and antiproliferative effect of selenylated imidazo[1,2-a]pyridines on hepatocellular carcinoma HepG2 cells and in vivo.
Dos Santos DC, Rafique J, Saba S, Almeida GM, Siminski T, Pádua C, Filho DW, Zamoner A, Braga AL, Pedrosa RC, Ourique F. Dos Santos DC, et al. Among authors: pedrosa rc. J Biochem Mol Toxicol. 2021 Mar;35(3):e22663. doi: 10.1002/jbt.22663. Epub 2020 Oct 30. J Biochem Mol Toxicol. 2021. PMID: 33125183
IP-Se-06, a Selenylated Imidazo[1,2-a]pyridine, Modulates Intracellular Redox State and Causes Akt/mTOR/HIF-1α and MAPK Signaling Inhibition, Promoting Antiproliferative Effect and Apoptosis in Glioblastoma Cells.
Dos Santos DC, Rafique J, Saba S, Grinevicius VMAS, Filho DW, Zamoner A, Braga AL, Pedrosa RC, Ourique F. Dos Santos DC, et al. Among authors: pedrosa rc. Oxid Med Cell Longev. 2022 Mar 22;2022:3710449. doi: 10.1155/2022/3710449. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35360199 Free PMC article.
Novel selenylated imidazo[1,2-a]pyridines for breast cancer chemotherapy: Inhibition of cell proliferation by Akt-mediated regulation, DNA cleavage and apoptosis.
Almeida GM, Rafique J, Saba S, Siminski T, Mota NSRS, Filho DW, Braga AL, Pedrosa RC, Ourique F. Almeida GM, et al. Among authors: pedrosa rc. Biochem Biophys Res Commun. 2018 Sep 10;503(3):1291-1297. doi: 10.1016/j.bbrc.2018.07.039. Epub 2018 Jul 14. Biochem Biophys Res Commun. 2018. PMID: 30017191
In vivo antitumor activity of by-products of Passiflora edulis f. flavicarpa Deg. Rich in medium and long chain fatty acids evaluated through oxidative stress markers, cell cycle arrest and apoptosis induction.
Mota NSRS, Kviecinski MR, Zeferino RC, de Oliveira DA, Bretanha LC, Ferreira SRS, Micke GA, Filho DW, Pedrosa RC, Ourique F. Mota NSRS, et al. Among authors: pedrosa rc. Food Chem Toxicol. 2018 Aug;118:557-565. doi: 10.1016/j.fct.2018.06.010. Epub 2018 Jun 7. Food Chem Toxicol. 2018. PMID: 29886231
Piper nigrum ethanolic extract rich in piperamides causes ROS overproduction, oxidative damage in DNA leading to cell cycle arrest and apoptosis in cancer cells.
de Souza Grinevicius VM, Kviecinski MR, Santos Mota NS, Ourique F, Porfirio Will Castro LS, Andreguetti RR, Gomes Correia JF, Filho DW, Pich CT, Pedrosa RC. de Souza Grinevicius VM, et al. Among authors: pedrosa rc. J Ethnopharmacol. 2016 Aug 2;189:139-47. doi: 10.1016/j.jep.2016.05.020. Epub 2016 May 10. J Ethnopharmacol. 2016. PMID: 27178634 Free article.
Albendazole as a promising molecule for tumor control.
Castro LS, Kviecinski MR, Ourique F, Parisotto EB, Grinevicius VM, Correia JF, Wilhelm Filho D, Pedrosa RC. Castro LS, et al. Among authors: pedrosa rc. Redox Biol. 2016 Dec;10:90-99. doi: 10.1016/j.redox.2016.09.013. Epub 2016 Sep 22. Redox Biol. 2016. PMID: 27710854 Free PMC article.
144 results