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Reactive cysteine persulfides and S-polythiolation regulate oxidative stress and redox signaling.
Ida T, Sawa T, Ihara H, Tsuchiya Y, Watanabe Y, Kumagai Y, Suematsu M, Motohashi H, Fujii S, Matsunaga T, Yamamoto M, Ono K, Devarie-Baez NO, Xian M, Fukuto JM, Akaike T. Ida T, et al. Among authors: tsuchiya y. Proc Natl Acad Sci U S A. 2014 May 27;111(21):7606-11. doi: 10.1073/pnas.1321232111. Epub 2014 Apr 14. Proc Natl Acad Sci U S A. 2014. PMID: 24733942 Free PMC article.
1,4-Naphthoquinone activates the HSP90/HSF1 pathway through the S-arylation of HSP90 in A431 cells: Negative regulation of the redox signal transduction pathway by persulfides/polysulfides.
Abiko Y, Sha L, Shinkai Y, Unoki T, Luong NC, Tsuchiya Y, Watanabe Y, Hirose R, Akaike T, Kumagai Y. Abiko Y, et al. Among authors: tsuchiya y. Free Radic Biol Med. 2017 Mar;104:118-128. doi: 10.1016/j.freeradbiomed.2016.12.047. Epub 2016 Dec 31. Free Radic Biol Med. 2017. PMID: 28049024
Discovery and Mechanistic Characterization of Selective Inhibitors of H2S-producing Enzyme: 3-Mercaptopyruvate Sulfurtransferase (3MST) Targeting Active-site Cysteine Persulfide.
Hanaoka K, Sasakura K, Suwanai Y, Toma-Fukai S, Shimamoto K, Takano Y, Shibuya N, Terai T, Komatsu T, Ueno T, Ogasawara Y, Tsuchiya Y, Watanabe Y, Kimura H, Wang C, Uchiyama M, Kojima H, Okabe T, Urano Y, Shimizu T, Nagano T. Hanaoka K, et al. Among authors: tsuchiya y. Sci Rep. 2017 Jan 12;7:40227. doi: 10.1038/srep40227. Sci Rep. 2017. PMID: 28079151 Free PMC article.
1,195 results