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Nucleotide Excision Repair Lesion-Recognition Protein Rad4 Captures a Pre-Flipped Partner Base in a Benzo[a]pyrene-Derived DNA Lesion: How Structure Impacts the Binding Pathway.
Mu H, Geacintov NE, Min JH, Zhang Y, Broyde S. Mu H, et al. Chem Res Toxicol. 2017 Jun 19;30(6):1344-1354. doi: 10.1021/acs.chemrestox.7b00074. Epub 2017 May 15. Chem Res Toxicol. 2017. PMID: 28460163 Free PMC article.
This binding path differs significantly from the one deduced for the small cis-syn cyclobutane pyrimidine dimer lesion opposite mismatched thymines [ Mu , H. , ( 2015 ) Biochemistry , 54 ( 34 ), 5263 - 7 ]. The possibility of multiple paths that lead to productive b …
This binding path differs significantly from the one deduced for the small cis-syn cyclobutane pyrimidine dimer lesion opposite mismatched t …
Resistance of bulky DNA lesions to nucleotide excision repair can result from extensive aromatic lesion-base stacking interactions.
Reeves DA, Mu H, Kropachev K, Cai Y, Ding S, Kolbanovskiy A, Kolbanovskiy M, Chen Y, Krzeminski J, Amin S, Patel DJ, Broyde S, Geacintov NE. Reeves DA, et al. Among authors: mu h. Nucleic Acids Res. 2011 Nov 1;39(20):8752-64. doi: 10.1093/nar/gkr537. Epub 2011 Jul 15. Nucleic Acids Res. 2011. PMID: 21764772 Free PMC article.
Nucleotide excision repair of 2-acetylaminofluorene- and 2-aminofluorene-(C8)-guanine adducts: molecular dynamics simulations elucidate how lesion structure and base sequence context impact repair efficiencies.
Mu H, Kropachev K, Wang L, Zhang L, Kolbanovskiy A, Kolbanovskiy M, Geacintov NE, Broyde S. Mu H, et al. Nucleic Acids Res. 2012 Oct;40(19):9675-90. doi: 10.1093/nar/gks788. Epub 2012 Aug 16. Nucleic Acids Res. 2012. PMID: 22904073 Free PMC article.
1,380 results