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Page 1
Controlling Supramolecular Structures of Drugs by Light.
Wiest J, Kehrein J, Saedtler M, Schilling K, Cataldi E, Sotriffer CA, Holzgrabe U, Rasmussen T, Böttcher B, Cronin-Golomb M, Lehmann M, Jung N, Windbergs M, Meinel L. Wiest J, et al. Among authors: sotriffer ca. Mol Pharm. 2020 Dec 7;17(12):4704-4708. doi: 10.1021/acs.molpharmaceut.0c00720. Epub 2020 Oct 29. Mol Pharm. 2020. PMID: 33118829
1,4-Substituted 4-(1H)-pyridylene-hydrazone-type inhibitors of AChE, BuChE, and amyloid-β aggregation crossing the blood-brain barrier.
Prinz M, Parlar S, Bayraktar G, Alptüzün V, Erciyas E, Fallarero A, Karlsson D, Vuorela P, Burek M, Förster C, Turunc E, Armagan G, Yalcin A, Schiller C, Leuner K, Krug M, Sotriffer CA, Holzgrabe U. Prinz M, et al. Among authors: sotriffer ca. Eur J Pharm Sci. 2013 Jul 16;49(4):603-13. doi: 10.1016/j.ejps.2013.04.024. Epub 2013 May 2. Eur J Pharm Sci. 2013. PMID: 23643737
Mapping the pharmaceutical design space by amorphous ionic liquid strategies.
Wiest J, Saedtler M, Balk A, Merget B, Widmer T, Bruhn H, Raccuglia M, Walid E, Picard F, Stopper H, Dekant W, Lühmann T, Sotriffer C, Galli B, Holzgrabe U, Meinel L. Wiest J, et al. J Control Release. 2017 Dec 28;268:314-322. doi: 10.1016/j.jconrel.2017.10.040. Epub 2017 Oct 31. J Control Release. 2017. PMID: 29097303
A Long Residence Time Enoyl-Reductase Inhibitor Explores an Extended Binding Region with Isoenzyme-Dependent Tautomer Adaptation and Differential Substrate-Binding Loop Closure.
Eltschkner S, Kehrein J, Le TA, Davoodi S, Merget B, Basak S, Weinrich JD, Schiebel J, Tonge PJ, Engels B, Sotriffer C, Kisker C. Eltschkner S, et al. ACS Infect Dis. 2021 Apr 9;7(4):746-758. doi: 10.1021/acsinfecdis.0c00437. Epub 2021 Mar 12. ACS Infect Dis. 2021. PMID: 33710875 Free PMC article.
Predicting Bile and Lipid Interaction for Drug Substances.
Schlauersbach J, Kehrein J, Hanio S, Galli B, Harlacher C, Heidenreich C, Lenz B, Sotriffer C, Meinel L. Schlauersbach J, et al. Mol Pharm. 2022 Aug 1;19(8):2868-2876. doi: 10.1021/acs.molpharmaceut.2c00227. Epub 2022 Jul 1. Mol Pharm. 2022. PMID: 35776440
105 results