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Cryo-EM structure of the human MLL1 core complex bound to the nucleosome.
Park SH, Ayoub A, Lee YT, Xu J, Kim H, Zheng W, Zhang B, Sha L, An S, Zhang Y, Cianfrocco MA, Su M, Dou Y, Cho US. Park SH, et al. Among authors: an s. Nat Commun. 2019 Dec 5;10(1):5540. doi: 10.1038/s41467-019-13550-2. Nat Commun. 2019. PMID: 31804488 Free PMC article.
An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase.
Raiymbek G, An S, Khurana N, Gopinath S, Larkin A, Biswas S, Trievel RC, Cho US, Ragunathan K. Raiymbek G, et al. Among authors: an s. Elife. 2020 Mar 20;9:e53155. doi: 10.7554/eLife.53155. Elife. 2020. PMID: 32195666 Free PMC article.
For example, a protein found in yeast called Epe1 helps reactivate large groups of genes after cell division, effectively 're-setting' the yeast's genome and eliminating past memories of the genes being inactive. ...This observation contrasts with the prevailing view where …
For example, a protein found in yeast called Epe1 helps reactivate large groups of genes after cell division, effectively 're-setting' the y …
Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functions for the inner pocket.
Chik JK, Moiseeva V, Goel PK, Meinen BA, Koldewey P, An S, Mellone BG, Subramanian L, Cho US. Chik JK, et al. Among authors: an s. J Biol Chem. 2019 Sep 20;294(38):14119-14134. doi: 10.1074/jbc.RA119.008464. Epub 2019 Jul 31. J Biol Chem. 2019. PMID: 31366733 Free PMC article.
At its C terminus, CENP-C harbors a conserved cupin domain that has an established role in protein dimerization. Although the crystal structure of the Saccharomyces cerevisiae Mif2(CENP-C) cupin domain has been determined, centromeric organization and kinetochore compositi …
At its C terminus, CENP-C harbors a conserved cupin domain that has an established role in protein dimerization. Although the crystal …
4,042 results