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Depletion of LAG-3+ T Cells Translated to Pharmacology and Improvement in Psoriasis Disease Activity: A Phase I Randomized Study of mAb GSK2831781.
Ellis J, J B Marks D, Srinivasan N, Barrett C, Hopkins TG, Richards A, Fuhr R, Albayaty M, Coenen M, Liefaard L, Leavens K, Nevin KL, Tang S, Hughes SA, Fortunato L, Edwards K, Cui Y, Anselm R, Delves CJ, Charles E, Feeney M, Webb TM, Brett SJ, Schmidt TS, Stone J, Savage COS, Wisniacki N, Tarzi RM. Ellis J, et al. Among authors: schmidt ts. Clin Pharmacol Ther. 2021 May;109(5):1293-1303. doi: 10.1002/cpt.2091. Epub 2020 Nov 24. Clin Pharmacol Ther. 2021. PMID: 33113155 Free PMC article. Clinical Trial.
Characterisation of the clinical and activated T cell response to repeat delayed-type hypersensitivity skin challenges in human subjects, with KLH and PPD, as a potential model to test T cell-targeted therapies.
Belson A, Schmidt T, Fernando D, Hardes K, Scott N, Brett S, Clark D, Oliveira JJ, Davis B, McHugh S, Stone J. Belson A, et al. Inflamm Res. 2016 May;65(5):389-404. doi: 10.1007/s00011-016-0923-4. Epub 2016 Mar 11. Inflamm Res. 2016. PMID: 26969026 Clinical Trial.
Paternal microbiome perturbations impact offspring fitness.
Argaw-Denboba A, Schmidt TSB, Di Giacomo M, Ranjan B, Devendran S, Mastrorilli E, Lloyd CT, Pugliese D, Paribeni V, Dabin J, Pisaniello A, Espinola S, Crevenna A, Ghosh S, Humphreys N, Boruc O, Sarkies P, Zimmermann M, Bork P, Hackett JA. Argaw-Denboba A, et al. Among authors: schmidt tsb. Nature. 2024 May;629(8012):652-659. doi: 10.1038/s41586-024-07336-w. Epub 2024 May 1. Nature. 2024. PMID: 38693261 Free PMC article.
Improving ecosystem health in highly altered river basins: a generalized framework and its application to the Mississippi-Atchafalaya River Basin.
McLellan EL, Suttles KM, Bouska KL, Ellis JH, Flotemersch JE, Goff M, Golden HE, Hill RA, Hohman TR, Keerthi S, Keim RF, Kleiss BA, Lark TJ, Piazza BP, Renfro AA, Robertson DM, Schilling KE, Schmidt TS, Waite IR. McLellan EL, et al. Among authors: schmidt ts. Front Environ Sci. 2024 Feb 22;12:1-19. doi: 10.3389/fenvs.2024.1332934. Front Environ Sci. 2024. PMID: 38516348
Functional and evolutionary significance of unknown genes from uncultivated taxa.
Rodríguez Del Río Á, Giner-Lamia J, Cantalapiedra CP, Botas J, Deng Z, Hernández-Plaza A, Munar-Palmer M, Santamaría-Hernando S, Rodríguez-Herva JJ, Ruscheweyh HJ, Paoli L, Schmidt TSB, Sunagawa S, Bork P, López-Solanilla E, Coelho LP, Huerta-Cepas J. Rodríguez Del Río Á, et al. Among authors: schmidt tsb. Nature. 2024 Feb;626(7998):377-384. doi: 10.1038/s41586-023-06955-z. Epub 2023 Dec 18. Nature. 2024. PMID: 38109938 Free PMC article.
SPIRE: a Searchable, Planetary-scale mIcrobiome REsource.
Schmidt TSB, Fullam A, Ferretti P, Orakov A, Maistrenko OM, Ruscheweyh HJ, Letunic I, Duan Y, Van Rossum T, Sunagawa S, Mende DR, Finn RD, Kuhn M, Pedro Coelho L, Bork P. Schmidt TSB, et al. Nucleic Acids Res. 2024 Jan 5;52(D1):D777-D783. doi: 10.1093/nar/gkad943. Nucleic Acids Res. 2024. PMID: 37897342 Free PMC article.
98 results