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S224 Presents a Catalytic Trade-off in PLP-Dependent l-Lanthionine Synthase from Fusobacterium nucleatum.
Biochemistry. 2020 Nov 10;59(44):4250-4261. doi: 10.1021/acs.biochem.0c00683. Epub 2020 Oct 28.
Biochemistry. 2020.
PMID: 33112129
A Fold Type II PLP-Dependent Enzyme from Fusobacterium nucleatum Functions as a Serine Synthase and Cysteine Synthase.
Darbyshire AL, Mothersole RG, Wolthers KR.
Darbyshire AL, et al.
Biochemistry. 2021 Feb 23;60(7):524-536. doi: 10.1021/acs.biochem.0c00902. Epub 2021 Feb 4.
Biochemistry. 2021.
PMID: 33539704
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Steady-state and pre-steady state kinetic analysis of ornithine 4,5-aminomutase.
Darbyshire AL, Makins C, Wolthers KR.
Darbyshire AL, et al.
Methods Enzymol. 2022;669:173-195. doi: 10.1016/bs.mie.2021.11.016. Epub 2021 Dec 23.
Methods Enzymol. 2022.
PMID: 35644171
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Biosynthesis of meso-lanthionine in Fusobacterium nucleatum.
Darbyshire A, Mothersole R, Wolthers KR.
Darbyshire A, et al.
Arch Biochem Biophys. 2023 Jul 15;743:109666. doi: 10.1016/j.abb.2023.109666. Epub 2023 Jun 16.
Arch Biochem Biophys. 2023.
PMID: 37329940
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Expanding the β-substitution reactions of serine synthase through mutagenesis of aromatic active site residues.
Darbyshire AL, Wolthers KR.
Darbyshire AL, et al.
Arch Biochem Biophys. 2023 Sep 15;746:109727. doi: 10.1016/j.abb.2023.109727. Epub 2023 Aug 23.
Arch Biochem Biophys. 2023.
PMID: 37625767
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Characterization of a Structurally Distinct ATP-Dependent Reactivating Factor of Adenosylcobalamin-Dependent Lysine 5,6-Aminomutase.
Darbyshire AL, Wolthers KR.
Darbyshire AL, et al.
Biochemistry. 2024 Apr 2;63(7):913-925. doi: 10.1021/acs.biochem.3c00653. Epub 2024 Mar 12.
Biochemistry. 2024.
PMID: 38471967
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