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Increased estrogen to androgen ratio enhances immunoglobulin levels and impairs B cell function in male mice.
Aguilar-Pimentel JA, Cho YL, Gerlini R, Calzada-Wack J, Wimmer M, Mayer-Kuckuk P, Adler T, Schmidt-Weber CB, Busch DH, Fuchs H, Gailus-Durner V, Ollert M, Hrabě de Angelis M, Ohlsson C, Poutanen M, Teperino R, Strauss L. Aguilar-Pimentel JA, et al. Among authors: ohlsson c. Sci Rep. 2020 Oct 27;10(1):18334. doi: 10.1038/s41598-020-75059-9. Sci Rep. 2020. PMID: 33110090 Free PMC article.
Seminal vesicles and urinary bladder as sites of aromatization of androgens in men, evidenced by a CYP19A1-driven luciferase reporter mouse and human tissue specimens.
Strauss L, Rantakari P, Sjögren K, Salminen A, Lauren E, Kallio J, Damdimopoulou P, Boström M, Boström PJ, Pakarinen P, Zhang F, Kujala P, Ohlsson C, Mäkelä S, Poutanen M. Strauss L, et al. Among authors: ohlsson c. FASEB J. 2013 Apr;27(4):1342-50. doi: 10.1096/fj.12-219048. Epub 2012 Dec 13. FASEB J. 2013. PMID: 23239821
The bone-sparing effects of estrogen and WNT16 are independent of each other.
Movérare-Skrtic S, Wu J, Henning P, Gustafsson KL, Sjögren K, Windahl SH, Koskela A, Tuukkanen J, Börjesson AE, Lagerquist MK, Lerner UH, Zhang FP, Gustafsson JÅ, Poutanen M, Ohlsson C. Movérare-Skrtic S, et al. Among authors: ohlsson c. Proc Natl Acad Sci U S A. 2015 Dec 1;112(48):14972-7. doi: 10.1073/pnas.1520408112. Epub 2015 Nov 16. Proc Natl Acad Sci U S A. 2015. PMID: 26627248 Free PMC article.
Liver lipid metabolism is altered by increased circulating estrogen to androgen ratio in male mouse.
Vehmas AP, Adam M, Laajala TD, Kastenmüller G, Prehn C, Rozman J, Ohlsson C, Fuchs H, Hrabě de Angelis M, Gailus-Durner V, Elo LL, Aittokallio T, Adamski J, Corthals G, Poutanen M, Strauss L. Vehmas AP, et al. Among authors: ohlsson c. J Proteomics. 2016 Feb 5;133:66-75. doi: 10.1016/j.jprot.2015.12.009. Epub 2015 Dec 9. J Proteomics. 2016. PMID: 26691839
The Hydroxysteroid (17β) Dehydrogenase Family Gene HSD17B12 Is Involved in the Prostaglandin Synthesis Pathway, the Ovarian Function, and Regulation of Fertility.
Kemiläinen H, Adam M, Mäki-Jouppila J, Damdimopoulou P, Damdimopoulos AE, Kere J, Hovatta O, Laajala TD, Aittokallio T, Adamski J, Ryberg H, Ohlsson C, Strauss L, Poutanen M. Kemiläinen H, et al. Among authors: ohlsson c. Endocrinology. 2016 Oct;157(10):3719-3730. doi: 10.1210/en.2016-1252. Epub 2016 Aug 4. Endocrinology. 2016. PMID: 27490311
Increased adipose tissue aromatase activity improves insulin sensitivity and reduces adipose tissue inflammation in male mice.
Ohlsson C, Hammarstedt A, Vandenput L, Saarinen N, Ryberg H, Windahl SH, Farman HH, Jansson JO, Movérare-Skrtic S, Smith U, Zhang FP, Poutanen M, Hedjazifar S, Sjögren K. Ohlsson C, et al. Am J Physiol Endocrinol Metab. 2017 Oct 1;313(4):E450-E462. doi: 10.1152/ajpendo.00093.2017. Epub 2017 Jun 27. Am J Physiol Endocrinol Metab. 2017. PMID: 28655716 Free PMC article.
751 results