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Reply to Liu et al.: The Andean EGLN1 adaptive allele could be a loss of function variant that increases HIF1-α in skeletal muscle.
Brutsaert TD, Kiyamu M, Revollendo GE, Isherwood JL, Lee FS, Rivera-Ch M, Leon-Velarde F, Ghosh S, Bigham AW. Brutsaert TD, et al. Proc Natl Acad Sci U S A. 2020 Nov 24;117(47):29286-29287. doi: 10.1073/pnas.2012199117. Epub 2020 Oct 27. Proc Natl Acad Sci U S A. 2020. PMID: 33109724 Free PMC article. No abstract available.
Andean and Tibetan patterns of adaptation to high altitude.
Bigham AW, Wilson MJ, Julian CG, Kiyamu M, Vargas E, Leon-Velarde F, Rivera-Chira M, Rodriquez C, Browne VA, Parra E, Brutsaert TD, Moore LG, Shriver MD. Bigham AW, et al. Among authors: brutsaert td. Am J Hum Biol. 2013 Mar-Apr;25(2):190-7. doi: 10.1002/ajhb.22358. Epub 2013 Jan 24. Am J Hum Biol. 2013. PMID: 23348729 Free article.
LINE-1 and EPAS1 DNA methylation associations with high-altitude exposure.
Childebayeva A, Jones TR, Goodrich JM, Leon-Velarde F, Rivera-Chira M, Kiyamu M, Brutsaert TD, Dolinoy DC, Bigham AW. Childebayeva A, et al. Among authors: brutsaert td. Epigenetics. 2019 Jan;14(1):1-15. doi: 10.1080/15592294.2018.1561117. Epub 2019 Jan 9. Epigenetics. 2019. PMID: 30574831 Free PMC article.
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