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Genetically modified mouse models to help fight COVID-19.
Gurumurthy CB, Quadros RM, Richardson GP, Poluektova LY, Mansour SL, Ohtsuka M. Gurumurthy CB, et al. Among authors: richardson gp. Nat Protoc. 2020 Dec;15(12):3777-3787. doi: 10.1038/s41596-020-00403-2. Epub 2020 Oct 26. Nat Protoc. 2020. PMID: 33106680 Free PMC article. Review.
Easi-CRISPR: a robust method for one-step generation of mice carrying conditional and insertion alleles using long ssDNA donors and CRISPR ribonucleoproteins.
Quadros RM, Miura H, Harms DW, Akatsuka H, Sato T, Aida T, Redder R, Richardson GP, Inagaki Y, Sakai D, Buckley SM, Seshacharyulu P, Batra SK, Behlke MA, Zeiner SA, Jacobi AM, Izu Y, Thoreson WB, Urness LD, Mansour SL, Ohtsuka M, Gurumurthy CB. Quadros RM, et al. Among authors: richardson gp. Genome Biol. 2017 May 17;18(1):92. doi: 10.1186/s13059-017-1220-4. Genome Biol. 2017. PMID: 28511701 Free PMC article.
Large-scale annotated dataset for cochlear hair cell detection and classification.
Buswinka CJ, Rosenberg DB, Simikyan RG, Osgood RT, Fernandez K, Nitta H, Hayashi Y, Liberman LW, Nguyen E, Yildiz E, Kim J, Jarysta A, Renauld J, Wesson E, Wang H, Thapa P, Bordiga P, McMurtry N, Llamas J, Kitcher SR, López-Porras AI, Cui R, Behnammanesh G, Bird JE, Ballesteros A, Vélez-Ortega AC, Edge ASB, Deans MR, Gnedeva K, Shrestha BR, Manor U, Zhao B, Ricci AJ, Tarchini B, Basch ML, Stepanyan R, Landegger LD, Rutherford MA, Liberman MC, Walters BJ, Kros CJ, Richardson GP, Cunningham LL, Indzhykulian AA. Buswinka CJ, et al. Among authors: richardson gp. Sci Data. 2024 Apr 23;11(1):416. doi: 10.1038/s41597-024-03218-y. Sci Data. 2024. PMID: 38653806 Free PMC article.
Charge and lipophilicity are required for effective block of the hair-cell mechano-electrical transducer channel by FM1-43 and its derivatives.
Derudas M, O'Reilly M, Kirkwood NK, Kenyon EJ, Grimsey S, Kitcher SR, Workman S, Bull JC, Ward SE, Kros CJ, Richardson GP. Derudas M, et al. Among authors: richardson gp. Front Cell Dev Biol. 2023 Oct 10;11:1247324. doi: 10.3389/fcell.2023.1247324. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 37900280 Free PMC article.
Large-scale annotated dataset for cochlear hair cell detection and classification.
Buswinka CJ, Rosenberg DB, Simikyan RG, Osgood RT, Fernandez K, Nitta H, Hayashi Y, Liberman LW, Nguyen E, Yildiz E, Kim J, Jarysta A, Renauld J, Wesson E, Thapa P, Bordiga P, McMurtry N, Llamas J, Kitcher SR, López-Porras AI, Cui R, Behnammanesh G, Bird JE, Ballesteros A, Vélez-Ortega AC, Edge AS, Deans MR, Gnedeva K, Shrestha BR, Manor U, Zhao B, Ricci AJ, Tarchini B, Basch M, Stepanyan RS, Landegger LD, Rutherford M, Liberman MC, Walters BJ, Kros CJ, Richardson GP, Cunningham LL, Indzhykulian AA. Buswinka CJ, et al. Among authors: richardson gp. bioRxiv [Preprint]. 2023 Sep 1:2023.08.30.553559. doi: 10.1101/2023.08.30.553559. bioRxiv. 2023. PMID: 37693382 Free PMC article. Updated. Preprint.
Visualizing Collagen Fibrils in the Cochlea's Tectorial and Basilar Membranes Using a Fluorescently Labeled Collagen-Binding Protein Fragment.
de Sousa Lobo Ferreira Querido R, Ji X, Lakha R, Goodyear RJ, Richardson GP, Vizcarra CL, Olson ES. de Sousa Lobo Ferreira Querido R, et al. Among authors: richardson gp. J Assoc Res Otolaryngol. 2023 Apr;24(2):147-157. doi: 10.1007/s10162-023-00889-z. Epub 2023 Feb 1. J Assoc Res Otolaryngol. 2023. PMID: 36725777 Free PMC article.
AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness.
Jeng JY, Carlton AJ, Goodyear RJ, Chinowsky C, Ceriani F, Johnson SL, Sung TC, Dayn Y, Richardson GP, Bowl MR, Brown SDM, Manor U, Marcotti W. Jeng JY, et al. Among authors: richardson gp. Mol Ther Methods Clin Dev. 2022 Jul 31;26:355-370. doi: 10.1016/j.omtm.2022.07.012. eCollection 2022 Sep 8. Mol Ther Methods Clin Dev. 2022. PMID: 36034774 Free PMC article.
Identification of a series of hair-cell MET channel blockers that protect against aminoglycoside-induced ototoxicity.
Kenyon EJ, Kirkwood NK, Kitcher SR, Goodyear RJ, Derudas M, Cantillon DM, Baxendale S, de la Vega de León A, Mahieu VN, Osgood RT, Wilson CD, Bull JC, Waddell SJ, Whitfield TT, Ward SE, Kros CJ, Richardson GP. Kenyon EJ, et al. Among authors: richardson gp. JCI Insight. 2021 Apr 8;6(7):e145704. doi: 10.1172/jci.insight.145704. JCI Insight. 2021. PMID: 33735112 Free PMC article.
134 results