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Linagliptin Ameliorates Hepatic Steatosis via Non-Canonical Mechanisms in Mice Treated with a Dual Inhibitor of Insulin Receptor and IGF-1 Receptor.
Okuyama T, Shirakawa J, Tajima K, Ino Y, Vethe H, Togashi Y, Kyohara M, Inoue R, Miyashita D, Li J, Goto N, Ichikawa T, Yamasaki S, Ohnuma H, Takayanagi R, Kimura Y, Hirano H, Terauchi Y. Okuyama T, et al. Among authors: li j. Int J Mol Sci. 2020 Oct 22;21(21):7815. doi: 10.3390/ijms21217815. Int J Mol Sci. 2020. PMID: 33105604 Free PMC article.
Uncoupling protein 2 and aldolase B impact insulin release by modulating mitochondrial function and Ca2+ release from the ER.
Inoue R, Tsuno T, Togashi Y, Okuyama T, Sato A, Nishiyama K, Kyohara M, Li J, Fukushima S, Kin T, Miyashita D, Shiba Y, Atobe Y, Kiyonari H, Bando K, Shapiro AMJ, Funakoshi K, Kulkarni RN, Terauchi Y, Shirakawa J. Inoue R, et al. Among authors: li j. iScience. 2022 Jun 14;25(7):104603. doi: 10.1016/j.isci.2022.104603. eCollection 2022 Jul 15. iScience. 2022. PMID: 35800776 Free PMC article.
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