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The Mdm2 and p53 genes are conserved in the Arachnids.
Lane DP, Cheok CF, Brown CJ, Madhumalar A, Ghadessy FJ, Verma C. Lane DP, et al. Among authors: brown cj. Cell Cycle. 2010 Feb 15;9(4):748-54. doi: 10.4161/cc.9.4.10616. Epub 2010 Feb 12. Cell Cycle. 2010. PMID: 20160485
Inhibition of nutlin-resistant HDM2 mutants by stapled peptides.
Wei SJ, Joseph T, Chee S, Li L, Yurlova L, Zolghadr K, Brown C, Lane D, Verma C, Ghadessy F. Wei SJ, et al. PLoS One. 2013 Nov 20;8(11):e81068. doi: 10.1371/journal.pone.0081068. eCollection 2013. PLoS One. 2013. PMID: 24278380 Free PMC article.
The fluorescent two-hybrid assay to screen for protein-protein interaction inhibitors in live cells: targeting the interaction of p53 with Mdm2 and Mdm4.
Yurlova L, Derks M, Buchfellner A, Hickson I, Janssen M, Morrison D, Stansfield I, Brown CJ, Ghadessy FJ, Lane DP, Rothbauer U, Zolghadr K, Krausz E. Yurlova L, et al. Among authors: brown cj. J Biomol Screen. 2014 Apr;19(4):516-25. doi: 10.1177/1087057113518067. Epub 2014 Jan 29. J Biomol Screen. 2014. PMID: 24476585
Structure of a stapled peptide antagonist bound to nutlin-resistant Mdm2.
Chee SM, Wongsantichon J, Soo Tng Q, Robinson R, Joseph TL, Verma C, Lane DP, Brown CJ, Ghadessy FJ. Chee SM, et al. Among authors: brown cj. PLoS One. 2014 Aug 12;9(8):e104914. doi: 10.1371/journal.pone.0104914. eCollection 2014. PLoS One. 2014. PMID: 25115702 Free PMC article.
942 results