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Unacylated-Ghrelin Impairs Hippocampal Neurogenesis and Memory in Mice and Is Altered in Parkinson's Dementia in Humans.
Hornsby AKE, Buntwal L, Carisi MC, Santos VV, Johnston F, Roberts LD, Sassi M, Mequinion M, Stark R, Reichenbach A, Lockie SH, Siervo M, Howell O, Morgan AH, Wells T, Andrews ZB, Burn DJ, Davies JS. Hornsby AKE, et al. Among authors: howell o. Cell Rep Med. 2020 Oct 20;1(7):100120. doi: 10.1016/j.xcrm.2020.100120. Cell Rep Med. 2020. PMID: 33103129 Free PMC article.
Calorie restriction activates new adult born olfactory-bulb neurones in a ghrelin-dependent manner but acyl-ghrelin does not enhance subventricular zone neurogenesis.
Ratcliff M, Rees D, McGrady S, Buntwal L, Hornsby AKE, Bayliss J, Kent BA, Bussey T, Saksida L, Beynon AL, Howell OW, Morgan AH, Sun Y, Andrews ZB, Wells T, Davies JS. Ratcliff M, et al. J Neuroendocrinol. 2019 Jul;31(7):e12755. doi: 10.1111/jne.12755. Epub 2019 Jun 24. J Neuroendocrinol. 2019. PMID: 31179562
Neuropeptide Y is important for basal and seizure-induced precursor cell proliferation in the hippocampus.
Howell OW, Silva S, Scharfman HE, Sosunov AA, Zaben M, Shtaya A, McKhann G 2nd, Herzog H, Laskowski A, Gray WP. Howell OW, et al. Neurobiol Dis. 2007 Apr;26(1):174-88. doi: 10.1016/j.nbd.2006.12.014. Epub 2006 Dec 30. Neurobiol Dis. 2007. PMID: 17317195
We have shown that neuropeptide Y (NPY) regulates neurogenesis in the normal dentate gyrus (DG) via Y(1) receptors (Howell, O.W., Scharfman, H.E., Herzog, H., Sundstrom, L.E., Beck-Sickinger, A. and Gray, W.P. (2003) Neuropeptide Y is neuroproliferative for post-nat …
We have shown that neuropeptide Y (NPY) regulates neurogenesis in the normal dentate gyrus (DG) via Y(1) receptors (Howell, O. …
68 results