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Expression of protein kinase HIPK2 is subject to a quality control mechanism that acts during translation and requires its kinase activity to prevent degradation of nascent HIPK2.
Müller JP, Scholl S, Kunick C, Klempnauer KH. Müller JP, et al. Among authors: klempnauer kh. Biochim Biophys Acta Mol Cell Res. 2021 Jan;1868(1):118894. doi: 10.1016/j.bbamcr.2020.118894. Epub 2020 Oct 19. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 33091504 Free article.
Tumor suppressor protein Pdcd4 inhibits translation of p53 mRNA.
Wedeken L, Singh P, Klempnauer KH. Wedeken L, et al. Among authors: klempnauer kh. J Biol Chem. 2011 Dec 16;286(50):42855-62. doi: 10.1074/jbc.M111.269456. Epub 2011 Oct 27. J Biol Chem. 2011. PMID: 22033922 Free PMC article.
Withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPβ.
Falkenberg KD, Jakobs A, Matern JC, Dörner W, Uttarkar S, Trentmann A, Steinmann S, Coulibaly A, Schomburg C, Mootz HD, Schmidt TJ, Klempnauer KH. Falkenberg KD, et al. Among authors: klempnauer kh. Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1349-1358. doi: 10.1016/j.bbamcr.2017.05.003. Epub 2017 May 2. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28476645 Free article.
129 results