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Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology.
Hou X, Watzlawik JO, Cook C, Liu CC, Kang SS, Lin WL, DeTure M, Heckman MG, Diehl NN, Al-Shaikh FSH, Walton RL, Ross OA, Melrose HL, Ertekin-Taner N, Bu G, Petrucelli L, Fryer JD, Murray ME, Dickson DW, Fiesel FC, Springer W. Hou X, et al. Among authors: diehl nn. Alzheimers Dement. 2020 Oct 8;17(3):417-30. doi: 10.1002/alz.12198. Online ahead of print. Alzheimers Dement. 2020. PMID: 33090691 Free PMC article.
Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease.
Liu CC, Yamazaki Y, Heckman MG, Martens YA, Jia L, Yamazaki A, Diehl NN, Zhao J, Zhao N, DeTure M, Davis MD, Felton LM, Qiao W, Li Y, Li H, Fu Y, Wang N, Wren M, Aikawa T, Holm ML, Oue H, Linares C, Allen M, Carrasquillo MM, Murray ME, Petersen RC, Ertekin-Taner N, Dickson DW, Kanekiyo T, Bu G. Liu CC, et al. Among authors: diehl nn. Alzheimers Dement. 2020 Oct;16(10):1372-1383. doi: 10.1002/alz.12104. Epub 2020 Aug 22. Alzheimers Dement. 2020. PMID: 32827351 Free PMC article.
Parkinson's disease susceptibility variants and severity of Lewy body pathology.
Heckman MG, Kasanuki K, Diehl NN, Koga S, Soto A, Murray ME, Dickson DW, Ross OA. Heckman MG, et al. Among authors: diehl nn. Parkinsonism Relat Disord. 2017 Nov;44:79-84. doi: 10.1016/j.parkreldis.2017.09.009. Epub 2017 Sep 11. Parkinsonism Relat Disord. 2017. PMID: 28917824 Free PMC article.
Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease.
Hou X, Fiesel FC, Truban D, Castanedes Casey M, Lin WL, Soto AI, Tacik P, Rousseau LG, Diehl NN, Heckman MG, Lorenzo-Betancor O, Ferrer I, Arbelo JM, Steele JC, Farrer MJ, Cornejo-Olivas M, Torres L, Mata IF, Graff-Radford NR, Wszolek ZK, Ross OA, Murray ME, Dickson DW, Springer W. Hou X, et al. Among authors: diehl nn. Autophagy. 2018;14(8):1404-1418. doi: 10.1080/15548627.2018.1461294. Epub 2018 Jul 28. Autophagy. 2018. PMID: 29947276 Free PMC article.
APOE ε4 is associated with severity of Lewy body pathology independent of Alzheimer pathology.
Dickson DW, Heckman MG, Murray ME, Soto AI, Walton RL, Diehl NN, van Gerpen JA, Uitti RJ, Wszolek ZK, Ertekin-Taner N, Knopman DS, Petersen RC, Graff-Radford NR, Boeve BF, Bu G, Ferman TJ, Ross OA. Dickson DW, et al. Among authors: diehl nn. Neurology. 2018 Sep 18;91(12):e1182-e1195. doi: 10.1212/WNL.0000000000006212. Epub 2018 Aug 24. Neurology. 2018. PMID: 30143564 Free PMC article.
APOE ε2 is associated with increased tau pathology in primary tauopathy.
Zhao N, Liu CC, Van Ingelgom AJ, Linares C, Kurti A, Knight JA, Heckman MG, Diehl NN, Shinohara M, Martens YA, Attrebi ON, Petrucelli L, Fryer JD, Wszolek ZK, Graff-Radford NR, Caselli RJ, Sanchez-Contreras MY, Rademakers R, Murray ME, Koga S, Dickson DW, Ross OA, Bu G. Zhao N, et al. Among authors: diehl nn. Nat Commun. 2018 Oct 22;9(1):4388. doi: 10.1038/s41467-018-06783-0. Nat Commun. 2018. PMID: 30348994 Free PMC article.
LRRK2 variation and dementia with Lewy bodies.
Heckman MG, Soto-Ortolaza AI, Contreras MYS, Murray ME, Pedraza O, Diehl NN, Walton R, Labbé C, Lorenzo-Betancor O, Uitti RJ, van Gerpen J, Ertekin-Taner N, Smith GE, Kantarci K, Savica R, Jones DT, Graff-Radford J, Knopman DS, Lowe VJ, Jack CR Jr, Petersen RC, Parisi JE, Rademakers R, Wszolek ZK, Graff-Radford NR, Ferman TJ, Dickson DW, Boeve BF, Ross OA. Heckman MG, et al. Among authors: diehl nn. Parkinsonism Relat Disord. 2016 Oct;31:98-103. doi: 10.1016/j.parkreldis.2016.07.015. Epub 2016 Jul 29. Parkinsonism Relat Disord. 2016. PMID: 27521182 Free PMC article.
185 results