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Mitophagy alterations in Alzheimer's disease are associated with granulovacuolar degeneration and early tau pathology.
Hou X, Watzlawik JO, Cook C, Liu CC, Kang SS, Lin WL, DeTure M, Heckman MG, Diehl NN, Al-Shaikh FSH, Walton RL, Ross OA, Melrose HL, Ertekin-Taner N, Bu G, Petrucelli L, Fryer JD, Murray ME, Dickson DW, Fiesel FC, Springer W. Hou X, et al. Among authors: bu g. Alzheimers Dement. 2020 Oct 8;17(3):417-30. doi: 10.1002/alz.12198. Online ahead of print. Alzheimers Dement. 2020. PMID: 33090691 Free PMC article.
The low density lipoprotein receptor regulates the level of central nervous system human and murine apolipoprotein E but does not modify amyloid plaque pathology in PDAPP mice.
Fryer JD, Demattos RB, McCormick LM, O'Dell MA, Spinner ML, Bales KR, Paul SM, Sullivan PM, Parsadanian M, Bu G, Holtzman DM. Fryer JD, et al. Among authors: bu g. J Biol Chem. 2005 Jul 8;280(27):25754-9. doi: 10.1074/jbc.M502143200. Epub 2005 May 11. J Biol Chem. 2005. PMID: 15888448 Free article.
Neuronal clearance of amyloid-β by endocytic receptor LRP1.
Kanekiyo T, Cirrito JR, Liu CC, Shinohara M, Li J, Schuler DR, Shinohara M, Holtzman DM, Bu G. Kanekiyo T, et al. Among authors: bu g. J Neurosci. 2013 Dec 4;33(49):19276-83. doi: 10.1523/JNEUROSCI.3487-13.2013. J Neurosci. 2013. PMID: 24305823 Free PMC article.
ApoE variant p.V236E is associated with markedly reduced risk of Alzheimer's disease.
Medway CW, Abdul-Hay S, Mims T, Ma L, Bisceglio G, Zou F, Pankratz S, Sando SB, Aasly JO, Barcikowska M, Siuda J, Wszolek ZK, Ross OA, Carrasquillo M, Dickson DW, Graff-Radford N, Petersen RC, Ertekin-Taner N, Morgan K, Bu G, Younkin SG. Medway CW, et al. Among authors: bu g. Mol Neurodegener. 2014 Mar 10;9:11. doi: 10.1186/1750-1326-9-11. Mol Neurodegener. 2014. PMID: 24607147 Free PMC article.
Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer's disease.
Shinohara M, Fujioka S, Murray ME, Wojtas A, Baker M, Rovelet-Lecrux A, Rademakers R, Das P, Parisi JE, Graff-Radford NR, Petersen RC, Dickson DW, Bu G. Shinohara M, et al. Among authors: bu g. Brain. 2014 May;137(Pt 5):1533-49. doi: 10.1093/brain/awu046. Epub 2014 Mar 12. Brain. 2014. PMID: 24625695 Free PMC article.
566 results