Lucas R - Search Results

1

Optogenetic Control of the BMP Signaling Pathway.

Humphreys PA, Woods S, Smith CA, Bates N, Cain SA, Lucas R, Kimber SJ. Humphreys PA, et al. Among authors: lucas r. ACS Synth Biol. 2020 Nov 20;9(11):3067-3078. doi: 10.1021/acssynbio.0c00315. Epub 2020 Oct 21. ACS Synth Biol. 2020. PMID: 33084303 Free PMC article.

2

Cartilage repair using human embryonic stem cell-derived chondroprogenitors.

Cheng A, Kapacee Z, Peng J, Lu S, Lucas RJ, Hardingham TE, Kimber SJ. Cheng A, et al. Stem Cells Transl Med. 2014 Nov;3(11):1287-94. doi: 10.5966/sctm.2014-0101. Epub 2014 Oct 1. Stem Cells Transl Med. 2014. PMID: 25273540 Free PMC article.

3

A live cell assay of GPCR coupling allows identification of optogenetic tools for controlling Go and Gi signaling.

Ballister ER, Rodgers J, Martial F, Lucas RJ. Ballister ER, et al. Among authors: lucas rj. BMC Biol. 2018 Jan 16;16(1):10. doi: 10.1186/s12915-017-0475-2. BMC Biol. 2018. PMID: 29338718 Free PMC article.

4

Reproducible and sustained regulation of Gαs signalling using a metazoan opsin as an optogenetic tool.

Bailes HJ, Zhuang LY, Lucas RJ. Bailes HJ, et al. PLoS One. 2012;7(1):e30774. doi: 10.1371/journal.pone.0030774. Epub 2012 Jan 24. PLoS One. 2012. PMID: 22292038 Free PMC article.

5

Optogenetic interrogation reveals separable G-protein-dependent and -independent signalling linking G-protein-coupled receptors to the circadian oscillator.

Bailes HJ, Milosavljevic N, Zhuang LY, Gerrard EJ, Nishiguchi T, Ozawa T, Lucas RJ. Bailes HJ, et al. BMC Biol. 2017 May 15;15(1):40. doi: 10.1186/s12915-017-0380-8. BMC Biol. 2017. PMID: 28506231 Free PMC article.

6

Divergent G-protein selectivity across melanopsins from mice and humans.

McDowell RJ, Rodgers J, Milosavljevic N, Lucas RJ. McDowell RJ, et al. J Cell Sci. 2022 Mar 15;135(6):jcs258474. doi: 10.1242/jcs.258474. Epub 2022 Mar 21. J Cell Sci. 2022. PMID: 35274137 Free PMC article.

7

Encephalic photoreception and phototactic response in the troglobiont Somalian blind cavefish Phreatichthys andruzzii.

Tarttelin EE, Frigato E, Bellingham J, Di Rosa V, Berti R, Foulkes NS, Lucas RJ, Bertolucci C. Tarttelin EE, et al. Among authors: lucas rj. J Exp Biol. 2012 Aug 15;215(Pt 16):2898-903. doi: 10.1242/jeb.071084. J Exp Biol. 2012. PMID: 22837464 Free PMC article.

8

Using a bistable animal opsin for switchable and scalable optogenetic inhibition of neurons.

Rodgers J, Bano-Otalora B, Belle MDC, Paul S, Hughes R, Wright P, McDowell R, Milosavljevic N, Orlowska-Feuer P, Martial FP, Wynne J, Ballister ER, Storchi R, Allen AE, Brown T, Lucas RJ. Rodgers J, et al. Among authors: lucas rj. EMBO Rep. 2021 May 5;22(5):e51866. doi: 10.15252/embr.202051866. Epub 2021 Mar 2. EMBO Rep. 2021. PMID: 33655694 Free PMC article.

9

Viral Transduction of Human Rod Opsin or Channelrhodopsin Variants to Mouse ON Bipolar Cells Does Not Impact Retinal Anatomy or Cause Measurable Death in the Targeted Cells.

Wright P, Rodgers J, Wynne J, Bishop PN, Lucas RJ, Milosavljevic N. Wright P, et al. Int J Mol Sci. 2021 Dec 3;22(23):13111. doi: 10.3390/ijms222313111. Int J Mol Sci. 2021. PMID: 34884916 Free PMC article.

10

Modulating signalling lifetime to optimise a prototypical animal opsin for optogenetic applications.

Rodgers J, Wright P, Ballister ER, Hughes RB, Storchi R, Wynne J, Martial FP, Lucas RJ. Rodgers J, et al. Among authors: lucas rj. Pflugers Arch. 2023 Dec;475(12):1387-1407. doi: 10.1007/s00424-023-02879-9. Epub 2023 Dec 1. Pflugers Arch. 2023. PMID: 38036775 Free PMC article.

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