Wells JA - Search Results

1

Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2.

Bracken CJ, Lim SA, Solomon P, Rettko NJ, Nguyen DP, Zha BS, Schaefer K, Byrnes JR, Zhou J, Lui I, Liu J, Pance K; QCRG Structural Biology Consortium; Zhou XX, Leung KK, Wells JA. Bracken CJ, et al. Among authors: wells ja. Nat Chem Biol. 2021 Jan;17(1):113-121. doi: 10.1038/s41589-020-00679-1. Epub 2020 Oct 20. Nat Chem Biol. 2021. PMID: 33082574 Free PMC article.

2

Reaching for high-hanging fruit in drug discovery at protein-protein interfaces.

Wells JA, McClendon CL. Wells JA, et al. Nature. 2007 Dec 13;450(7172):1001-9. doi: 10.1038/nature06526. Nature. 2007. PMID: 18075579 Review.

3

Nature-inspired design of motif-specific antibody scaffolds.

Koerber JT, Thomsen ND, Hannigan BT, Degrado WF, Wells JA. Koerber JT, et al. Among authors: wells ja. Nat Biotechnol. 2013 Oct;31(10):916-21. doi: 10.1038/nbt.2672. Epub 2013 Aug 18. Nat Biotechnol. 2013. PMID: 23955275 Free PMC article.

4

Unraveling the mechanism of cell death induced by chemical fibrils.

Julien O, Kampmann M, Bassik MC, Zorn JA, Venditto VJ, Shimbo K, Agard NJ, Shimada K, Rheingold AL, Stockwell BR, Weissman JS, Wells JA. Julien O, et al. Among authors: wells ja. Nat Chem Biol. 2014 Nov;10(11):969-76. doi: 10.1038/nchembio.1639. Epub 2014 Sep 28. Nat Chem Biol. 2014. PMID: 25262416 Free PMC article.

5

CryptoSite: Expanding the Druggable Proteome by Characterization and Prediction of Cryptic Binding Sites.

Cimermancic P, Weinkam P, Rettenmaier TJ, Bichmann L, Keedy DA, Woldeyes RA, Schneidman-Duhovny D, Demerdash ON, Mitchell JC, Wells JA, Fraser JS, Sali A. Cimermancic P, et al. Among authors: wells ja. J Mol Biol. 2016 Feb 22;428(4):709-719. doi: 10.1016/j.jmb.2016.01.029. Epub 2016 Feb 5. J Mol Biol. 2016. PMID: 26854760 Free PMC article.

6

Ligand-binding domains of nuclear receptors facilitate tight control of split CRISPR activity.

Nguyen DP, Miyaoka Y, Gilbert LA, Mayerl SJ, Lee BH, Weissman JS, Conklin BR, Wells JA. Nguyen DP, et al. Among authors: wells ja. Nat Commun. 2016 Jul 1;7:12009. doi: 10.1038/ncomms12009. Nat Commun. 2016. PMID: 27363581 Free PMC article.

7

A reactivity-based probe of the intracellular labile ferrous iron pool.

Spangler B, Morgan CW, Fontaine SD, Vander Wal MN, Chang CJ, Wells JA, Renslo AR. Spangler B, et al. Among authors: wells ja. Nat Chem Biol. 2016 Sep;12(9):680-5. doi: 10.1038/nchembio.2116. Epub 2016 Jul 4. Nat Chem Biol. 2016. PMID: 27376690 Free PMC article.

8

Engineering a light-activated caspase-3 for precise ablation of neurons in vivo.

Smart AD, Pache RA, Thomsen ND, Kortemme T, Davis GW, Wells JA. Smart AD, et al. Among authors: wells ja. Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):E8174-E8183. doi: 10.1073/pnas.1705064114. Epub 2017 Sep 11. Proc Natl Acad Sci U S A. 2017. PMID: 28893998 Free PMC article.

9

Engineering peptide ligase specificity by proteomic identification of ligation sites.

Weeks AM, Wells JA. Weeks AM, et al. Among authors: wells ja. Nat Chem Biol. 2018 Jan;14(1):50-57. doi: 10.1038/nchembio.2521. Epub 2017 Nov 20. Nat Chem Biol. 2018. PMID: 29155430 Free PMC article.

10

Human antibody-based chemically induced dimerizers for cell therapeutic applications.

Hill ZB, Martinko AJ, Nguyen DP, Wells JA. Hill ZB, et al. Among authors: wells ja. Nat Chem Biol. 2018 Feb;14(2):112-117. doi: 10.1038/nchembio.2529. Epub 2017 Dec 4. Nat Chem Biol. 2018. PMID: 29200207 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

515 results

Search Page