Booth DR - Search Results

1

Vitamin D and its Effects on DNA Methylation in Development, Aging, and Disease.

Ong LTC, Booth DR, Parnell GP. Ong LTC, et al. Among authors: booth dr. Mol Nutr Food Res. 2020 Dec;64(23):e2000437. doi: 10.1002/mnfr.202000437. Epub 2020 Oct 29. Mol Nutr Food Res. 2020. PMID: 33079481 Review.

2

Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk.

Ong LTC, Schibeci SD, Fewings NL, Booth DR, Parnell GP. Ong LTC, et al. Among authors: booth dr. Epigenetics Chromatin. 2021 Feb 4;14(1):9. doi: 10.1186/s13072-021-00383-x. Epigenetics Chromatin. 2021. PMID: 33541415 Free PMC article.

3

The latitude-dependent autoimmune disease risk genes ZMIZ1 and IRF8 regulate mononuclear phagocytic cell differentiation in response to vitamin D.

Parnell GP, Schibeci SD, Fewings NL, Afrasiabi A, Law SPL, Samaranayake S, Kh'ng JH, Fong YH, Brown DA, Liddle C, Stewart GJ, Booth DR. Parnell GP, et al. Among authors: booth dr. Hum Mol Genet. 2019 Jan 15;28(2):269-278. doi: 10.1093/hmg/ddy324. Hum Mol Genet. 2019. PMID: 30285234

4

Transcribed B lymphocyte genes and multiple sclerosis risk genes are underrepresented in Epstein-Barr Virus hypomethylated regions.

Ong LTC, Parnell GP, Afrasiabi A, Stewart GJ, Swaminathan S, Booth DR. Ong LTC, et al. Among authors: booth dr. Genes Immun. 2020 Feb;21(2):91-99. doi: 10.1038/s41435-019-0089-5. Epub 2019 Oct 16. Genes Immun. 2020. PMID: 31619767 Free PMC article.

5

The interaction of Multiple Sclerosis risk loci with Epstein-Barr virus phenotypes implicates the virus in pathogenesis.

Afrasiabi A, Parnell GP, Swaminathan S, Stewart GJ, Booth DR. Afrasiabi A, et al. Among authors: booth dr. Sci Rep. 2020 Jan 13;10(1):193. doi: 10.1038/s41598-019-55850-z. Sci Rep. 2020. PMID: 31932685 Free PMC article.

6

Regulation of the methylome in differentiation from adult stem cells may underpin vitamin D risk in MS.

Ong LTC, Parnell GP, Veale K, Stewart GJ, Liddle C, Booth DR. Ong LTC, et al. Among authors: booth dr. Genes Immun. 2020 Nov;21(5):335-347. doi: 10.1038/s41435-020-00114-4. Epub 2020 Oct 9. Genes Immun. 2020. PMID: 33037402

7

Ribosomal protein S6 mRNA is a biomarker upregulated in multiple sclerosis, downregulated by interferon treatment, and affected by season.

Parnell GP, Gatt PN, McKay FC, Schibeci S, Krupa M, Powell JE, Visscher PM, Montgomery GW, Lechner-Scott J, Broadley S, Liddle C, Slee M, Vucic S, Stewart GJ, Booth DR. Parnell GP, et al. Among authors: booth dr. Mult Scler. 2014 May;20(6):675-85. doi: 10.1177/1352458513507819. Epub 2013 Oct 14. Mult Scler. 2014. PMID: 24126065

8

The CYP27B1 variant associated with an increased risk of autoimmune disease is underexpressed in tolerizing dendritic cells.

Shahijanian F, Parnell GP, McKay FC, Gatt PN, Shojoei M, O'Connor KS, Schibeci SD, Brilot F, Liddle C, Batten M; ANZgene Multiple Sclerosis Genetics Consortium; Stewart GJ, Booth DR. Shahijanian F, et al. Among authors: booth dr. Hum Mol Genet. 2014 Mar 15;23(6):1425-34. doi: 10.1093/hmg/ddt529. Epub 2013 Oct 24. Hum Mol Genet. 2014. PMID: 24158849

9

Whole blood transcriptomic analysis to identify clinical biomarkers of drug response.

Parnell GP, Booth DR. Parnell GP, et al. Among authors: booth dr. Methods Mol Biol. 2014;1175:35-43. doi: 10.1007/978-1-4939-0956-8_3. Methods Mol Biol. 2014. PMID: 25150865

10

The Multiple Sclerosis (MS) Genetic Risk Factors Indicate both Acquired and Innate Immune Cell Subsets Contribute to MS Pathogenesis and Identify Novel Therapeutic Opportunities.

Parnell GP, Booth DR. Parnell GP, et al. Among authors: booth dr. Front Immunol. 2017 Apr 18;8:425. doi: 10.3389/fimmu.2017.00425. eCollection 2017. Front Immunol. 2017. PMID: 28458668 Free PMC article. Review.

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