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PLCγ1 suppression promotes the adaptation of KRAS-mutant lung adenocarcinomas to hypoxia.
Saliakoura M, Rossi Sebastiano M, Pozzato C, Heidel FH, Schnöder TM, Savic Prince S, Bubendorf L, Pinton P, A Schmid R, Baumgartner J, Freigang S, Berezowska SA, Rimessi A, Konstantinidou G. Saliakoura M, et al. Among authors: freigang s. Nat Cell Biol. 2020 Nov;22(11):1382-1395. doi: 10.1038/s41556-020-00592-8. Epub 2020 Oct 19. Nat Cell Biol. 2020. PMID: 33077911 Free PMC article.
TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis.
Zysset D, Weber B, Rihs S, Brasseit J, Freigang S, Riether C, Banz Y, Cerwenka A, Simillion C, Marques-Vidal P, Ochsenbein AF, Saurer L, Mueller C. Zysset D, et al. Among authors: freigang s. Nat Commun. 2016 Oct 20;7:13151. doi: 10.1038/ncomms13151. Nat Commun. 2016. PMID: 27762264 Free PMC article.
PPAR-γ regulates the effector function of human T helper 9 cells by promoting glycolysis.
Bertschi NL, Steck O, Luther F, Bazzini C, von Meyenn L, Schärli S, Vallone A, Felser A, Keller I, Friedli O, Freigang S, Begré N, Radonjic-Hoesli S, Lamos C, Gabutti MP, Benzaquen M, Laimer M, Simon D, Nuoffer JM, Schlapbach C. Bertschi NL, et al. Among authors: freigang s. Nat Commun. 2023 Apr 29;14(1):2471. doi: 10.1038/s41467-023-38233-x. Nat Commun. 2023. PMID: 37120582 Free PMC article.
TNIK signaling imprints CD8+ T cell memory formation early after priming.
Jaeger-Ruckstuhl CA, Hinterbrandner M, Höpner S, Correnti CE, Lüthi U, Friedli O, Freigang S, Al Sayed MF, Bührer ED, Amrein MA, Schürch CM, Radpour R, Riether C, Ochsenbein AF. Jaeger-Ruckstuhl CA, et al. Among authors: freigang s. Nat Commun. 2020 Apr 2;11(1):1632. doi: 10.1038/s41467-020-15413-7. Nat Commun. 2020. PMID: 32242021 Free PMC article.
52 results