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Cisplatin alkylating activity in zebrafish causes resistance to chorionic degradation and inhibition of osteogenesis.
Aquat Toxicol. 2020 Dec;229:105656. doi: 10.1016/j.aquatox.2020.105656. Epub 2020 Oct 13.
Aquat Toxicol. 2020.
PMID: 33075613
Free PMC article.
Anticancer Activity and In Vitro to In Vivo Mechanistic Recapitulation of Novel Ruthenium-Based Metallodrugs in the Zebrafish Model.
Karas BF, Hotz JM, Gural BM, Terez KR, DiBona VL, Côrte-Real L, Valente A, Buckley BT, Cooper KR.
Karas BF, et al. Among authors: hotz jm.
Toxicol Sci. 2021 Jul 16;182(1):29-43. doi: 10.1093/toxsci/kfab041.
Toxicol Sci. 2021.
PMID: 33822233
Free PMC article.
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Characterization and tissue localization of zebrafish homologs of the human ABCB1 multidrug transporter.
Robey RW, Robinson AN, Ali-Rahmani F, Huff LM, Lusvarghi S, Vahedi S, Hotz JM, Warner AC, Butcher D, Matta J, Edmondson EF, Lee TD, Roth JS, Lee OW, Shen M, Tanner K, Hall MD, Ambudkar SV, Gottesman MM.
Robey RW, et al. Among authors: hotz jm.
Sci Rep. 2021 Dec 17;11(1):24150. doi: 10.1038/s41598-021-03500-8.
Sci Rep. 2021.
PMID: 34921178
Free PMC article.
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ATP-binding cassette transporters at the zebrafish blood-brain barrier and the potential utility of the zebrafish as an in vivo model.
Hotz JM, Thomas JR, Katz EN, Robey RW, Horibata S, Gottesman MM.
Hotz JM, et al.
Cancer Drug Resist. 2021;4(3):620-633. doi: 10.20517/cdr.2021.35. Epub 2021 May 25.
Cancer Drug Resist. 2021.
PMID: 34308273
Free PMC article.
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Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms.
Patel RP, Kuhn S, Yin D, Hotz JM, Maher FA, Robey RW, Gottesman MM, Horibata S.
Patel RP, et al. Among authors: hotz jm.
Transl Oncol. 2021 Jan;14(1):100917. doi: 10.1016/j.tranon.2020.100917. Epub 2020 Oct 22.
Transl Oncol. 2021.
PMID: 33129114
Free PMC article.
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