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Reactivating latent HIV with PKC agonists induces resistance to apoptosis and is associated with phosphorylation and activation of BCL2.
French AJ, Natesampillai S, Krogman A, Correia C, Peterson KL, Alto A, Chandrasekar AP, Misra A, Li Y, Kaufmann SH, Badley AD, Cummins NW. French AJ, et al. Among authors: natesampillai s. PLoS Pathog. 2020 Oct 19;16(10):e1008906. doi: 10.1371/journal.ppat.1008906. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33075109 Free PMC article.
Isolation of a TRAIL antagonist from the serum of HIV-infected patients.
Schnepple DJ, Shepard B, Bren GD, Cummins NW, Natesampillai S, Trushin S, Algeciras-Schimnich A, Meng XW, Sainski AM, Rizza SA, Kaufmann SH, Badley AD. Schnepple DJ, et al. Among authors: natesampillai s. J Biol Chem. 2011 Oct 14;286(41):35742-35754. doi: 10.1074/jbc.M111.274639. Epub 2011 Aug 22. J Biol Chem. 2011. PMID: 21859711 Free PMC article.
Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation.
Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, Cummins NW, Correia C, Meng XW, Tarara JE, Ramirez-Alvarado M, Katzmann DJ, Ochsenbauer C, Kappes JC, Kaufmann SH, Badley AD. Sainski AM, et al. Among authors: natesampillai s. J Cell Biol. 2014 Sep 29;206(7):867-76. doi: 10.1083/jcb.201405051. Epub 2014 Sep 22. J Cell Biol. 2014. PMID: 25246614 Free PMC article.
Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size.
Cummins NW, Sainski AM, Dai H, Natesampillai S, Pang YP, Bren GD, de Araujo Correia MCM, Sampath R, Rizza SA, O'Brien D, Yao JD, Kaufmann SH, Badley AD. Cummins NW, et al. Among authors: natesampillai s. J Virol. 2016 Mar 28;90(8):4032-4048. doi: 10.1128/JVI.03179-15. Print 2016 Apr. J Virol. 2016. PMID: 26842479 Free PMC article.
24 results