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Neutral Sphingomyelinase is an Affective Valence-Dependent Regulator of Learning and Memory.
Kalinichenko LS, Abdel-Hafiz L, Wang AL, Mühle C, Rösel N, Schumacher F, Kleuser B, Smaga I, Frankowska M, Filip M, Schaller G, Richter-Schmidinger T, Lenz B, Gulbins E, Kornhuber J, Oliveira AWC, Barros M, Huston JP, Müller CP. Kalinichenko LS, et al. Among authors: abdel hafiz l. Cereb Cortex. 2021 Jan 5;31(2):1316-1333. doi: 10.1093/cercor/bhaa298. Cereb Cortex. 2021. PMID: 33043975
Neutral ceramidase is a marker for cognitive performance in rats and monkeys.
Kalinichenko LS, Wang AL, Mühle C, Abdel-Hafiz L, Gulbins E, Kornhuber J, Oliveira AWC, Barros M, Huston JP, Müller CP. Kalinichenko LS, et al. Among authors: abdel hafiz l. Pharmacol Rep. 2021 Feb;73(1):73-84. doi: 10.1007/s43440-020-00159-2. Epub 2020 Sep 16. Pharmacol Rep. 2021. PMID: 32936422 Free PMC article.
Adult alcohol drinking and emotional tone are mediated by neutral sphingomyelinase during development in males.
Kalinichenko LS, Mühle C, Jia T, Anderheiden F, Datz M, Eberle AL, Eulenburg V, Granzow J, Hofer M, Hohenschild J, Huber SE, Kämpf S, Kogias G, Lacatusu L, Lugmair C, Taku SM, Meixner D, Sembritzki NK, Praetner M, Rhein C, Sauer C, Scholz J, Ulrich F, Valenta F, Weigand E, Werner M, Tay N, Mc Veigh CJ, Haase J, Wang AL, Abdel-Hafiz L, Huston JP, Smaga I, Frankowska M, Filip M, Lourdusamy A, Kirchner P, Ekici AB, Marx LM, Suresh NP, Frischknecht R, Fejtova A, Saied EM, Arenz C, Bozec A, Wank I, Kreitz S, Hess A, Bäuerle T, Ledesma MD, Mitroi DN, Miranda AM, Oliveira TG, Lenz B, Schumann G, Kornhuber J, Müller CP. Kalinichenko LS, et al. Among authors: abdel hafiz l. Cereb Cortex. 2023 Jan 5;33(3):844-864. doi: 10.1093/cercor/bhac106. Cereb Cortex. 2023. PMID: 35296883
Neutral sphingomyelinase mediates the co-morbidity trias of alcohol abuse, major depression and bone defects.
Kalinichenko LS, Mühle C, Jia T, Anderheiden F, Datz M, Eberle AL, Eulenburg V, Granzow J, Hofer M, Hohenschild J, Huber SE, Kämpf S, Kogias G, Lacatusu L, Lugmair C, Taku SM, Meixner D, Tesch N, Praetner M, Rhein C, Sauer C, Scholz J, Ulrich F, Valenta F, Weigand E, Werner M, Tay N, Mc Veigh CJ, Haase J, Wang AL, Abdel-Hafiz L, Huston JP, Smaga I, Frankowska M, Filip M, Lourdusamy A, Kirchner P, Ekici AB, Marx LM, Suresh NP, Frischknecht R, Fejtova A, Saied EM, Arenz C, Bozec A, Wank I, Kreitz S, Hess A, Bäuerle T, Ledesma MD, Mitroi DN, Miranda AM, Oliveira TG, Gulbins E, Lenz B, Schumann G, Kornhuber J, Müller CP. Kalinichenko LS, et al. Among authors: abdel hafiz l. Mol Psychiatry. 2021 Dec;26(12):7403-7416. doi: 10.1038/s41380-021-01304-w. Epub 2021 Sep 28. Mol Psychiatry. 2021. PMID: 34584229 Free PMC article.
Promnestic effects of intranasally applied pregnenolone in rats.
Abdel-Hafiz L, Chao OY, Huston JP, Nikolaus S, Spieler RE, de Souza Silva MA, Mattern C. Abdel-Hafiz L, et al. Neurobiol Learn Mem. 2016 Sep;133:185-195. doi: 10.1016/j.nlm.2016.07.012. Epub 2016 Jul 14. Neurobiol Learn Mem. 2016. PMID: 27423520
Intranasal pregnenolone increases acetylcholine in frontal cortex, hippocampus, and amygdala-Preferentially in the hemisphere ipsilateral to the injected nostril.
Fazari B, Ilieva Decheva C, González García V, Abdel-Hafiz L, Nikolaus S, Hollenberg CP, Huston JP, de Souza Silva MA, Mattern C. Fazari B, et al. Among authors: abdel hafiz l. J Neurochem. 2020 Apr;153(2):189-202. doi: 10.1111/jnc.14923. Epub 2019 Dec 12. J Neurochem. 2020. PMID: 31755558 Free article.
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