Del Valle JR - Search Results

1

STING regulates BCR signaling in normal and malignant B cells.

Tang CA, Lee AC, Chang S, Xu Q, Shao A, Lo Y, Spalek WT, Pinilla-Ibarz JA, Del Valle JR, Hu CA. Tang CA, et al. Among authors: del valle jr. Cell Mol Immunol. 2021 Apr;18(4):1016-1031. doi: 10.1038/s41423-020-00552-0. Epub 2020 Sep 30. Cell Mol Immunol. 2021. PMID: 32999453 Free PMC article.

2

Overexpression of TCL1 activates the endoplasmic reticulum stress response: a novel mechanism of leukemic progression in mice.

Kriss CL, Pinilla-Ibarz JA, Mailloux AW, Powers JJ, Tang CH, Kang CW, Zanesi N, Epling-Burnette PK, Sotomayor EM, Croce CM, Del Valle JR, Hu CC. Kriss CL, et al. Among authors: del valle jr. Blood. 2012 Aug 2;120(5):1027-38. doi: 10.1182/blood-2011-11-394346. Epub 2012 Jun 12. Blood. 2012. PMID: 22692508 Free PMC article.

3

Inhibition of ER stress-associated IRE-1/XBP-1 pathway reduces leukemic cell survival.

Tang CH, Ranatunga S, Kriss CL, Cubitt CL, Tao J, Pinilla-Ibarz JA, Del Valle JR, Hu CC. Tang CH, et al. Among authors: del valle jr. J Clin Invest. 2014 Jun;124(6):2585-98. doi: 10.1172/JCI73448. Epub 2014 May 8. J Clin Invest. 2014. PMID: 24812669 Free PMC article.

4

Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells.

Tang CH, Zundell JA, Ranatunga S, Lin C, Nefedova Y, Del Valle JR, Hu CC. Tang CH, et al. Among authors: del valle jr. Cancer Res. 2016 Apr 15;76(8):2137-52. doi: 10.1158/0008-5472.CAN-15-1885. Epub 2016 Mar 7. Cancer Res. 2016. PMID: 26951929 Free PMC article.

5

Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization.

Tang CH, Chang S, Paton AW, Paton JC, Gabrilovich DI, Ploegh HL, Del Valle JR, Hu CC. Tang CH, et al. Among authors: del valle jr. J Cell Biol. 2018 May 7;217(5):1739-1755. doi: 10.1083/jcb.201709137. Epub 2018 Mar 6. J Cell Biol. 2018. PMID: 29511123 Free PMC article.

6

Secretory IgM Exacerbates Tumor Progression by Inducing Accumulations of MDSCs in Mice.

Tang CH, Chang S, Hashimoto A, Chen YJ, Kang CW, Mato AR, Del Valle JR, Gabrilovich DI, Hu CC. Tang CH, et al. Among authors: del valle jr. Cancer Immunol Res. 2018 Jun;6(6):696-710. doi: 10.1158/2326-6066.CIR-17-0582. Epub 2018 Apr 12. Cancer Immunol Res. 2018. PMID: 29650518 Free PMC article.

7

Structural Tailoring of a Novel Fluorescent IRE-1 RNase Inhibitor to Precisely Control Its Activity.

Shao A, Kang CW, Tang CH, Cain CF, Xu Q, Phoumyvong CM, Del Valle JR, Hu CC. Shao A, et al. Among authors: del valle jr. J Med Chem. 2019 Jun 13;62(11):5404-5413. doi: 10.1021/acs.jmedchem.9b00269. Epub 2019 May 22. J Med Chem. 2019. PMID: 31083990 Free PMC article.

8

Development of Tumor-Targeting IRE-1 Inhibitors for B-cell Cancer Therapy.

Shao A, Xu Q, Spalek WT, Cain CF, Kang CW, Tang CA, Del Valle JR, Hu CA. Shao A, et al. Among authors: del valle jr. Mol Cancer Ther. 2020 Dec;19(12):2432-2444. doi: 10.1158/1535-7163.MCT-20-0127. Epub 2020 Oct 13. Mol Cancer Ther. 2020. PMID: 33051362 Free PMC article.

9

Clarifying the translational potential of B-I09.

Del Valle JR, Betts BC, Yu XZ, Janssens S, Lambrecht BN, Simon MC, Hu CA. Del Valle JR, et al. Nat Chem Biol. 2020 Nov;16(11):1152. doi: 10.1038/s41589-020-00654-w. Nat Chem Biol. 2020. PMID: 33067597 Free PMC article. No abstract available.

10

IRE-1-Targeting Caged Prodrug with Endoplasmic Reticulum Stress-Inducing and XBP-1S-Inhibiting Activities for Cancer Therapy.

Shao A, Xu Q, Kang CW, Cain CF, Lee AC, Tang CA, Del Valle JR, Hu CA. Shao A, et al. Among authors: del valle jr. Mol Pharm. 2022 Apr 4;19(4):1059-1067. doi: 10.1021/acs.molpharmaceut.1c00639. Epub 2022 Mar 7. Mol Pharm. 2022. PMID: 35253431 Free PMC article.

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