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Targeted Inhibition of the NUP98-NSD1 Fusion Oncogene in Acute Myeloid Leukemia.
Mohanty S, Jyotsana N, Sharma A, Kloos A, Gabdoulline R, Othman B, Lai CK, Schottmann R, Mandhania M, Schmoellerl J, Grebien F, Ramsay E, Thomas A, Vornlocher HP, Ganser A, Thol F, Heuser M. Mohanty S, et al. Among authors: lai ck. Cancers (Basel). 2020 Sep 26;12(10):2766. doi: 10.3390/cancers12102766. Cancers (Basel). 2020. PMID: 32993115 Free PMC article.
Message from the void: MRD analysis from ctDNA.
Heuser M, Lai CK. Heuser M, et al. Among authors: lai ck. Blood. 2019 Jun 20;133(25):2631-2633. doi: 10.1182/blood-2019-04-901181. Blood. 2019. PMID: 31221791 Free article. No abstract available.
Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene.
Lai CK, Moon Y, Kuchenbauer F, Starzcynowski DT, Argiropoulos B, Yung E, Beer P, Schwarzer A, Sharma A, Park G, Leung M, Lin G, Vollett S, Fung S, Eaves CJ, Karsan A, Weng AP, Humphries RK, Heuser M. Lai CK, et al. PLoS One. 2014 Nov 17;9(11):e112671. doi: 10.1371/journal.pone.0112671. eCollection 2014. PLoS One. 2014. PMID: 25401736 Free PMC article.
Meis2 as a critical player in MN1-induced leukemia.
Lai CK, Norddahl GL, Maetzig T, Rosten P, Lohr T, Sanchez Milde L, von Krosigk N, Docking TR, Heuser M, Karsan A, Humphries RK. Lai CK, et al. Blood Cancer J. 2017 Sep 29;7(9):e613. doi: 10.1038/bcj.2017.86. Blood Cancer J. 2017. PMID: 28960191 Free PMC article.
Cell of origin in AML: susceptibility to MN1-induced transformation is regulated by the MEIS1/AbdB-like HOX protein complex.
Heuser M, Yun H, Berg T, Yung E, Argiropoulos B, Kuchenbauer F, Park G, Hamwi I, Palmqvist L, Lai CK, Leung M, Lin G, Chaturvedi A, Thakur BK, Iwasaki M, Bilenky M, Thiessen N, Robertson G, Hirst M, Kent D, Wilson NK, Göttgens B, Eaves C, Cleary ML, Marra M, Ganser A, Humphries RK. Heuser M, et al. Among authors: lai ck. Cancer Cell. 2011 Jul 12;20(1):39-52. doi: 10.1016/j.ccr.2011.06.020. Cancer Cell. 2011. PMID: 21741595 Free PMC article.
MiR-139-5p is a potent tumor suppressor in adult acute myeloid leukemia.
Krowiorz K, Ruschmann J, Lai C, Ngom M, Maetzig T, Martins V, Scheffold A, Schneider E, Pochert N, Miller C, Palmqvist L, Staffas A, Mulaw M, Bohl SR, Buske C, Heuser M, Kraus J, O'Neill K, Hansen CL, Petriv OI, Kestler H, Döhner H, Bullinger L, Döhner K, Humphries RK, Rouhi A, Kuchenbauer F. Krowiorz K, et al. Blood Cancer J. 2016 Dec 9;6(12):e508. doi: 10.1038/bcj.2016.110. Blood Cancer J. 2016. PMID: 27935579 Free PMC article. No abstract available.
531 results