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Ghrelin uses the GHS-R1a/Gi/cAMP pathway and induces differentiation only in mature osteoblasts. This ghrelin pathway is impaired in AIS patients.
Barre R, Beton N, Batut A, Accabled F, Sales de Gauzy J, Auriol F, Eddiry S, Tauber M, Laurencin S, Salles JP, Gennero I. Barre R, et al. Among authors: gennero i. Biochem Biophys Rep. 2020 Sep 11;24:100782. doi: 10.1016/j.bbrep.2020.100782. eCollection 2020 Dec. Biochem Biophys Rep. 2020. PMID: 32984555 Free PMC article.
Bone defects in LPA receptor genetically modified mice.
Salles JP, Laurencin-Dalicieux S, Conte-Auriol F, Briand-Mésange F, Gennero I. Salles JP, et al. Among authors: gennero i. Biochim Biophys Acta. 2013 Jan;1831(1):93-8. doi: 10.1016/j.bbalip.2012.07.018. Epub 2012 Jul 31. Biochim Biophys Acta. 2013. PMID: 22867754
44 results