Looker O - Search Results

1

Surface area-to-volume ratio, not cellular viscoelasticity, is the major determinant of red blood cell traversal through small channels.

Namvar A, Blanch AJ, Dixon MW, Carmo OMS, Liu B, Tiash S, Looker O, Andrew D, Chan LJ, Tham WH, Lee PVS, Rajagopal V, Tilley L. Namvar A, et al. Among authors: looker o. Cell Microbiol. 2021 Jan;23(1):e13270. doi: 10.1111/cmi.13270. Epub 2020 Oct 7. Cell Microbiol. 2021. PMID: 32981231 Free PMC article.

2

Specific expression and export of the Plasmodium falciparum Gametocyte EXported Protein-5 marks the gametocyte ring stage.

Tibúrcio M, Dixon MW, Looker O, Younis SY, Tilley L, Alano P. Tibúrcio M, et al. Among authors: looker o. Malar J. 2015 Aug 28;14:334. doi: 10.1186/s12936-015-0853-6. Malar J. 2015. PMID: 26315106 Free PMC article.

3

Reversible host cell remodeling underpins deformability changes in malaria parasite sexual blood stages.

Dearnley M, Chu T, Zhang Y, Looker O, Huang C, Klonis N, Yeoman J, Kenny S, Arora M, Osborne JM, Chandramohanadas R, Zhang S, Dixon MW, Tilley L. Dearnley M, et al. Among authors: looker o. Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4800-5. doi: 10.1073/pnas.1520194113. Epub 2016 Apr 11. Proc Natl Acad Sci U S A. 2016. PMID: 27071094 Free PMC article.

4

A new Python library to analyse skeleton images confirms malaria parasite remodelling of the red blood cell membrane skeleton.

Nunez-Iglesias J, Blanch AJ, Looker O, Dixon MW, Tilley L. Nunez-Iglesias J, et al. Among authors: looker o. PeerJ. 2018 Feb 15;6:e4312. doi: 10.7717/peerj.4312. eCollection 2018. PeerJ. 2018. PMID: 29472997 Free PMC article.

5

The knob protein KAHRP assembles into a ring-shaped structure that underpins virulence complex assembly.

Looker O, Blanch AJ, Liu B, Nunez-Iglesias J, McMillan PJ, Tilley L, Dixon MWA. Looker O, et al. PLoS Pathog. 2019 May 9;15(5):e1007761. doi: 10.1371/journal.ppat.1007761. eCollection 2019 May. PLoS Pathog. 2019. PMID: 31071194 Free PMC article.

6

Role of Plasmodium falciparum Protein GEXP07 in Maurer's Cleft Morphology, Knob Architecture, and P. falciparum EMP1 Trafficking.

McHugh E, Carmo OMS, Blanch A, Looker O, Liu B, Tiash S, Andrew D, Batinovic S, Low AJY, Cho HJ, McMillan P, Tilley L, Dixon MWA. McHugh E, et al. Among authors: looker o. mBio. 2020 Mar 17;11(2):e03320-19. doi: 10.1128/mBio.03320-19. mBio. 2020. PMID: 32184257 Free PMC article.

7

Multimodal imaging reveals membrane skeleton reorganisation during reticulocyte maturation and differences in dimple and rim regions of mature erythrocytes.

Blanch AJ, Nunez-Iglesias J, Namvar A, Menant S, Looker O, Rajagopal V, Tham WH, Tilley L, Dixon MWA. Blanch AJ, et al. Among authors: looker o. J Struct Biol X. 2021 Dec 8;6:100056. doi: 10.1016/j.yjsbx.2021.100056. eCollection 2022. J Struct Biol X. 2021. PMID: 34977554 Free PMC article.

8

The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts.

Parkyn Schneider M, Looker O, Rebelo M, Khoury DS, Dixon MWA, Oeuvray C, Crabb BS, McCarthy J, Gilson PR. Parkyn Schneider M, et al. Among authors: looker o. Front Cell Infect Microbiol. 2023 Jun 29;13:1211613. doi: 10.3389/fcimb.2023.1211613. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37457953 Free PMC article.

9

The Plasmodium falciparum parasitophorous vacuole protein P113 interacts with the parasite protein export machinery and maintains normal vacuole architecture.

Bullen HE, Sanders PR, Dans MG, Jonsdottir TK, Riglar DT, Looker O, Palmer CS, Kouskousis B, Charnaud SC, Triglia T, Gabriela M, Parkyn Schneider M, Chan JA, de Koning-Ward TF, Baum J, Kazura JW, Beeson JG, Cowman AF, Gilson PR, Crabb BS. Bullen HE, et al. Among authors: looker o. Mol Microbiol. 2022 May;117(5):1245-1262. doi: 10.1111/mmi.14904. Epub 2022 Apr 25. Mol Microbiol. 2022. PMID: 35403274 Free PMC article.

10

The Medicines for Malaria Venture Malaria Box contains inhibitors of protein secretion in Plasmodium falciparum blood stage parasites.

Looker O, Dans MG, Bullen HE, Sleebs BE, Crabb BS, Gilson PR. Looker O, et al. Traffic. 2022 Sep;23(9):442-461. doi: 10.1111/tra.12862. Epub 2022 Aug 15. Traffic. 2022. PMID: 36040075 Free PMC article.

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