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Cytosolic proteins regulate alpha-synuclein dissociation from presynaptic membranes.
Wislet-Gendebien S, D'Souza C, Kawarai T, St George-Hyslop P, Westaway D, Fraser P, Tandon A. Wislet-Gendebien S, et al. Among authors: d souza c, westaway d. J Biol Chem. 2006 Oct 27;281(43):32148-55. doi: 10.1074/jbc.M605965200. Epub 2006 Aug 22. J Biol Chem. 2006. PMID: 16926154 Free article. Retracted.
Presenilin 1 and presenilin 2 have differential effects on the stability and maturation of nicastrin in Mammalian brain.
Chen F, Tandon A, Sanjo N, Gu YJ, Hasegawa H, Arawaka S, Lee FJ, Ruan X, Mastrangelo P, Erdebil S, Wang L, Westaway D, Mount HT, Yankner B, Fraser PE, St George-Hyslop P. Chen F, et al. Among authors: westaway d. J Biol Chem. 2003 May 30;278(22):19974-9. doi: 10.1074/jbc.M210049200. Epub 2003 Mar 18. J Biol Chem. 2003. PMID: 12646573 Free article.
Carboxyl-terminal fragments of Alzheimer beta-amyloid precursor protein accumulate in restricted and unpredicted intracellular compartments in presenilin 1-deficient cells.
Chen F, Yang DS, Petanceska S, Yang A, Tandon A, Yu G, Rozmahel R, Ghiso J, Nishimura M, Zhang DM, Kawarai T, Levesque G, Mills J, Levesque L, Song YQ, Rogaeva E, Westaway D, Mount H, Gandy S, St George-Hyslop P, Fraser PE. Chen F, et al. Among authors: westaway d. J Biol Chem. 2000 Nov 24;275(47):36794-802. doi: 10.1074/jbc.M006986200. J Biol Chem. 2000. PMID: 10962005 Free article.
The PrP-like protein Doppel binds copper.
Qin K, Coomaraswamy J, Mastrangelo P, Yang Y, Lugowski S, Petromilli C, Prusiner SB, Fraser PE, Goldberg JM, Chakrabartty A, Westaway D. Qin K, et al. Among authors: westaway d. J Biol Chem. 2003 Mar 14;278(11):8888-96. doi: 10.1074/jbc.M210875200. Epub 2002 Dec 13. J Biol Chem. 2003. PMID: 12482851 Free article.
Contrary to expectations, Cu(II) induced a 26% reduction in the intrinsic fluorescence of Dpl(27-154) and a calculated K(d) for a single-site model of 0.16 +/- 0.08 microm. Other metals had minimal effects on fluorescence quenching. ...Fluorescence quenching and equilibriu …
Contrary to expectations, Cu(II) induced a 26% reduction in the intrinsic fluorescence of Dpl(27-154) and a calculated K(d) for a sin …
Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.
Drisaldi B, Coomaraswamy J, Mastrangelo P, Strome B, Yang J, Watts JC, Chishti MA, Marvi M, Windl O, Ahrens R, Major F, Sy MS, Kretzschmar H, Fraser PE, Mount HT, Westaway D. Drisaldi B, et al. Among authors: westaway d. J Biol Chem. 2004 Dec 31;279(53):55443-54. doi: 10.1074/jbc.M404794200. Epub 2004 Sep 29. J Biol Chem. 2004. PMID: 15459186 Free article.
221 results