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Angiopoietin-1 is required for Schlemm's canal development in mice and humans.
Thomson BR, Souma T, Tompson SW, Onay T, Kizhatil K, Siggs OM, Feng L, Whisenhunt KN, Yanovitch TL, Kalaydjieva L, Azmanov DN, Finzi S, Tanna CE, Hewitt AW, Mackey DA, Bradfield YS, Souzeau E, Javadiyan S, Wiggs JL, Pasutto F, Liu X, John SW, Craig JE, Jin J, Young TL, Quaggin SE. Thomson BR, et al. Among authors: quaggin se. J Clin Invest. 2017 Dec 1;127(12):4421-4436. doi: 10.1172/JCI95545. Epub 2017 Nov 6. J Clin Invest. 2017. PMID: 29106382 Free PMC article.
Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor.
Daly C, Qian X, Castanaro C, Pasnikowski E, Jiang X, Thomson BR, Quaggin SE, Papadopoulos N, Wei Y, Rudge JS, Thurston G, Yancopoulos GD, Davis S. Daly C, et al. Among authors: quaggin se. Sci Rep. 2018 Jan 11;8(1):505. doi: 10.1038/s41598-017-18912-8. Sci Rep. 2018. PMID: 29323190 Free PMC article.
Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP.
Souma T, Thomson BR, Heinen S, Carota IA, Yamaguchi S, Onay T, Liu P, Ghosh AK, Li C, Eremina V, Hong YK, Economides AN, Vestweber D, Peters KG, Jin J, Quaggin SE. Souma T, et al. Among authors: quaggin se. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1298-1303. doi: 10.1073/pnas.1714446115. Epub 2018 Jan 22. Proc Natl Acad Sci U S A. 2018. PMID: 29358379 Free PMC article.
Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development.
Ide S, Finer G, Maezawa Y, Onay T, Souma T, Scott R, Ide K, Akimoto Y, Li C, Ye M, Zhao X, Baba Y, Minamizuka T, Jin J, Takemoto M, Yokote K, Quaggin SE. Ide S, et al. Among authors: quaggin se. J Am Soc Nephrol. 2018 Dec;29(12):2795-2808. doi: 10.1681/ASN.2017121278. Epub 2018 Oct 30. J Am Soc Nephrol. 2018. PMID: 30377232 Free PMC article.
SVEP1 as a Genetic Modifier of TEK-Related Primary Congenital Glaucoma.
Young TL, Whisenhunt KN, Jin J, LaMartina SM, Martin SM, Souma T, Limviphuvadh V, Suri F, Souzeau E, Zhang X, Dan Y, Anagnos E, Carmona S, Jody NM, Stangel N, Higuchi EC, Huang SJ, Siggs OM, Simões MJ, Lawson BM, Martin JS, Elahi E, Narooie-Nejad M, Motlagh BF, Quaggin SE, Potter HD, Silva ED, Craig JE, Egas C, Maroofian R, Maurer-Stroh S, Bradfield YS, Tompson SW. Young TL, et al. Among authors: quaggin se. Invest Ophthalmol Vis Sci. 2020 Oct 1;61(12):6. doi: 10.1167/iovs.61.12.6. Invest Ophthalmol Vis Sci. 2020. PMID: 33027505 Free PMC article.
173 results