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Light-driven post-translational installation of reactive protein side chains.
Josephson B, Fehl C, Isenegger PG, Nadal S, Wright TH, Poh AWJ, Bower BJ, Giltrap AM, Chen L, Batchelor-McAuley C, Roper G, Arisa O, Sap JBI, Kawamura A, Baldwin AJ, Mohammed S, Compton RG, Gouverneur V, Davis BG. Josephson B, et al. Among authors: gouverneur v. Nature. 2020 Sep;585(7826):530-537. doi: 10.1038/s41586-020-2733-7. Epub 2020 Sep 23. Nature. 2020. PMID: 32968259
Selective Radical Trifluoromethylation of Native Residues in Proteins.
Imiołek M, Karunanithy G, Ng WL, Baldwin AJ, Gouverneur V, Davis BG. Imiołek M, et al. Among authors: gouverneur v. J Am Chem Soc. 2018 Feb 7;140(5):1568-1571. doi: 10.1021/jacs.7b10230. Epub 2018 Jan 22. J Am Chem Soc. 2018. PMID: 29301396 Free PMC article.
18F-Trifluoromethanesulfinate Enables Direct C-H 18F-Trifluoromethylation of Native Aromatic Residues in Peptides.
Kee CW, Tack O, Guibbal F, Wilson TC, Isenegger PG, Imiołek M, Verhoog S, Tilby M, Boscutti G, Ashworth S, Chupin J, Kashani R, Poh AWJ, Sosabowski JK, Macholl S, Plisson C, Cornelissen B, Willis MC, Passchier J, Davis BG, Gouverneur V. Kee CW, et al. Among authors: gouverneur v. J Am Chem Soc. 2020 Jan 22;142(3):1180-1185. doi: 10.1021/jacs.9b11709. Epub 2020 Jan 13. J Am Chem Soc. 2020. PMID: 31913613 Free PMC article.
Manual and automated Cu-mediated radiosynthesis of the PARP inhibitor [18F]olaparib.
Guibbal F, Isenegger PG, Wilson TC, Pacelli A, Mahaut D, Sap JBI, Taylor NJ, Verhoog S, Preshlock S, Hueting R, Cornelissen B, Gouverneur V. Guibbal F, et al. Among authors: gouverneur v. Nat Protoc. 2020 Apr;15(4):1525-1541. doi: 10.1038/s41596-020-0295-7. Epub 2020 Feb 28. Nat Protoc. 2020. PMID: 32111986
164 results