Rohatgi R - Search Results

1

A Membrane-Tethered Ubiquitination Pathway Regulates Hedgehog Signaling and Heart Development.

Kong JH, Young CB, Pusapati GV, Patel CB, Ho S, Krishnan A, Lin JI, Devine W, Moreau de Bellaing A, Athni TS, Aravind L, Gunn TM, Lo CW, Rohatgi R. Kong JH, et al. Among authors: rohatgi r. Dev Cell. 2020 Nov 23;55(4):432-449.e12. doi: 10.1016/j.devcel.2020.08.012. Epub 2020 Sep 22. Dev Cell. 2020. PMID: 32966817 Free PMC article.

2

Patched1 regulates hedgehog signaling at the primary cilium.

Rohatgi R, Milenkovic L, Scott MP. Rohatgi R, et al. Science. 2007 Jul 20;317(5836):372-6. doi: 10.1126/science.1139740. Science. 2007. PMID: 17641202

3

Patching the gaps in Hedgehog signalling.

Rohatgi R, Scott MP. Rohatgi R, et al. Nat Cell Biol. 2007 Sep;9(9):1005-9. doi: 10.1038/ncb435. Nat Cell Biol. 2007. PMID: 17762891

4

Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium.

Milenkovic L, Scott MP, Rohatgi R. Milenkovic L, et al. Among authors: rohatgi r. J Cell Biol. 2009 Nov 2;187(3):365-74. doi: 10.1083/jcb.200907126. Epub 2009 Oct 26. J Cell Biol. 2009. PMID: 19948480 Free PMC article.

5

Role of lipid metabolism in smoothened derepression in hedgehog signaling.

Yavari A, Nagaraj R, Owusu-Ansah E, Folick A, Ngo K, Hillman T, Call G, Rohatgi R, Scott MP, Banerjee U. Yavari A, et al. Among authors: rohatgi r. Dev Cell. 2010 Jul 20;19(1):54-65. doi: 10.1016/j.devcel.2010.06.007. Dev Cell. 2010. PMID: 20643350 Free PMC article.

6

A Smoothened-Evc2 complex transduces the Hedgehog signal at primary cilia.

Dorn KV, Hughes CE, Rohatgi R. Dorn KV, et al. Among authors: rohatgi r. Dev Cell. 2012 Oct 16;23(4):823-35. doi: 10.1016/j.devcel.2012.07.004. Epub 2012 Sep 13. Dev Cell. 2012. PMID: 22981989 Free PMC article.

7

Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling.

Nachtergaele S, Whalen DM, Mydock LK, Zhao Z, Malinauskas T, Krishnan K, Ingham PW, Covey DF, Siebold C, Rohatgi R. Nachtergaele S, et al. Among authors: rohatgi r. Elife. 2013 Oct 29;2:e01340. doi: 10.7554/eLife.01340. Elife. 2013. PMID: 24171105 Free PMC article.

8

Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling.

Niewiadomski P, Kong JH, Ahrends R, Ma Y, Humke EW, Khan S, Teruel MN, Novitch BG, Rohatgi R. Niewiadomski P, et al. Among authors: rohatgi r. Cell Rep. 2014 Jan 16;6(1):168-181. doi: 10.1016/j.celrep.2013.12.003. Epub 2013 Dec 27. Cell Rep. 2014. PMID: 24373970 Free PMC article.

9

EFCAB7 and IQCE regulate hedgehog signaling by tethering the EVC-EVC2 complex to the base of primary cilia.

Pusapati GV, Hughes CE, Dorn KV, Zhang D, Sugianto P, Aravind L, Rohatgi R. Pusapati GV, et al. Among authors: rohatgi r. Dev Cell. 2014 Mar 10;28(5):483-96. doi: 10.1016/j.devcel.2014.01.021. Epub 2014 Feb 27. Dev Cell. 2014. PMID: 24582806 Free PMC article.

10

G-protein-coupled receptors, Hedgehog signaling and primary cilia.

Mukhopadhyay S, Rohatgi R. Mukhopadhyay S, et al. Among authors: rohatgi r. Semin Cell Dev Biol. 2014 Sep;33:63-72. doi: 10.1016/j.semcdb.2014.05.002. Epub 2014 May 17. Semin Cell Dev Biol. 2014. PMID: 24845016 Free PMC article. Review.

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