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Single-Cell Genomics Reveals a Novel Cell State During Smooth Muscle Cell Phenotypic Switching and Potential Therapeutic Targets for Atherosclerosis in Mouse and Human.
Pan H, Xue C, Auerbach BJ, Fan J, Bashore AC, Cui J, Yang DY, Trignano SB, Liu W, Shi J, Ihuegbu CO, Bush EC, Worley J, Vlahos L, Laise P, Solomon RA, Connolly ES, Califano A, Sims PA, Zhang H, Li M, Reilly MP. Pan H, et al. Among authors: califano a. Circulation. 2020 Nov 24;142(21):2060-2075. doi: 10.1161/CIRCULATIONAHA.120.048378. Epub 2020 Sep 23. Circulation. 2020. PMID: 32962412 Free PMC article.
The transcriptional regulatory network of proneural glioma determines the genetic alterations selected during tumor progression.
Sonabend AM, Bansal M, Guarnieri P, Lei L, Amendolara B, Soderquist C, Leung R, Yun J, Kennedy B, Sisti J, Bruce S, Bruce R, Shakya R, Ludwig T, Rosenfeld S, Sims PA, Bruce JN, Califano A, Canoll P. Sonabend AM, et al. Among authors: califano a. Cancer Res. 2014 Mar 1;74(5):1440-1451. doi: 10.1158/0008-5472.CAN-13-2150. Epub 2014 Jan 3. Cancer Res. 2014. PMID: 24390738 Free PMC article.
A systems approach to drug discovery in Alzheimer's disease.
Shelanski M, Shin W, Aubry S, Sims P, Alvarez MJ, Califano A. Shelanski M, et al. Among authors: califano a. Neurotherapeutics. 2015 Jan;12(1):126-31. doi: 10.1007/s13311-014-0335-5. Neurotherapeutics. 2015. PMID: 25608936 Free PMC article. Review.
Experimental microdissection enables functional harmonisation of pancreatic cancer subtypes.
Maurer C, Holmstrom SR, He J, Laise P, Su T, Ahmed A, Hibshoosh H, Chabot JA, Oberstein PE, Sepulveda AR, Genkinger JM, Zhang J, Iuga AC, Bansal M, Califano A, Olive KP. Maurer C, et al. Among authors: califano a. Gut. 2019 Jun;68(6):1034-1043. doi: 10.1136/gutjnl-2018-317706. Epub 2019 Jan 18. Gut. 2019. PMID: 30658994 Free PMC article.
Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.
Elyada E, Bolisetty M, Laise P, Flynn WF, Courtois ET, Burkhart RA, Teinor JA, Belleau P, Biffi G, Lucito MS, Sivajothi S, Armstrong TD, Engle DD, Yu KH, Hao Y, Wolfgang CL, Park Y, Preall J, Jaffee EM, Califano A, Robson P, Tuveson DA. Elyada E, et al. Among authors: califano a. Cancer Discov. 2019 Aug;9(8):1102-1123. doi: 10.1158/2159-8290.CD-19-0094. Epub 2019 Jun 13. Cancer Discov. 2019. PMID: 31197017 Free PMC article.
Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations.
Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, Saito Y, Savage T, Wells RG, Mack M, Zender L, Arpaia N, Remotti HE, Rabadan R, Sims P, Leblond AL, Weber A, Riener MO, Stockwell BR, Gaublomme J, Llovet JM, Kalluri R, Michalopoulos GK, Seki E, Sia D, Chen X, Califano A, Schwabe RF. Affo S, et al. Among authors: califano a. Cancer Cell. 2021 Jun 14;39(6):866-882.e11. doi: 10.1016/j.ccell.2021.03.012. Epub 2021 Apr 29. Cancer Cell. 2021. PMID: 33930309 Free PMC article.
346 results