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A large-scale genome-lipid association map guides lipid identification.
Linke V, Overmyer KA, Miller IJ, Brademan DR, Hutchins PD, Trujillo EA, Reddy TR, Russell JD, Cushing EM, Schueler KL, Stapleton DS, Rabaglia ME, Keller MP, Gatti DM, Keele GR, Pham D, Broman KW, Churchill GA, Attie AD, Coon JJ. Linke V, et al. Among authors: keele gr. Nat Metab. 2020 Oct;2(10):1149-1162. doi: 10.1038/s42255-020-00278-3. Epub 2020 Sep 21. Nat Metab. 2020. PMID: 32958938 Free PMC article.
Genetic Fine-Mapping and Identification of Candidate Genes and Variants for Adiposity Traits in Outbred Rats.
Keele GR, Prokop JW, He H, Holl K, Littrell J, Deal A, Francic S, Cui L, Gatti DM, Broman KW, Tschannen M, Tsaih SW, Zagloul M, Kim Y, Baur B, Fox J, Robinson M, Levy S, Flister MJ, Mott R, Valdar W, Solberg Woods LC. Keele GR, et al. Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. Obesity (Silver Spring). 2018. PMID: 29193816 Free PMC article.
Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency.
Skelly DA, Czechanski A, Byers C, Aydin S, Spruce C, Olivier C, Choi K, Gatti DM, Raghupathy N, Keele GR, Stanton A, Vincent M, Dion S, Greenstein I, Pankratz M, Porter DK, Martin W, O'Connor C, Qin W, Harrill AH, Choi T, Churchill GA, Munger SC, Baker CL, Reinholdt LG. Skelly DA, et al. Among authors: keele gr. Cell Stem Cell. 2020 Sep 3;27(3):459-469.e8. doi: 10.1016/j.stem.2020.07.005. Epub 2020 Aug 13. Cell Stem Cell. 2020. PMID: 32795400 Free PMC article.
A Bayesian model selection approach to mediation analysis.
Crouse WL, Keele GR, Gastonguay MS, Churchill GA, Valdar W. Crouse WL, et al. Among authors: keele gr. PLoS Genet. 2022 May 9;18(5):e1010184. doi: 10.1371/journal.pgen.1010184. eCollection 2022 May. PLoS Genet. 2022. PMID: 35533209 Free PMC article.
Regulation of protein abundance in genetically diverse mouse populations.
Keele GR, Zhang T, Pham DT, Vincent M, Bell TA, Hock P, Shaw GD, Paulo JA, Munger SC, de Villena FP, Ferris MT, Gygi SP, Churchill GA. Keele GR, et al. Cell Genom. 2021 Oct 13;1(1):100003. doi: 10.1016/j.xgen.2021.100003. Epub 2021 Sep 3. Cell Genom. 2021. PMID: 36212994 Free PMC article.
Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression.
Yu Q, Liu X, Keller MP, Navarrete-Perea J, Zhang T, Fu S, Vaites LP, Shuken SR, Schmid E, Keele GR, Li J, Huttlin EL, Rashan EH, Simcox J, Churchill GA, Schweppe DK, Attie AD, Paulo JA, Gygi SP. Yu Q, et al. Among authors: keele gr. Nat Commun. 2023 Feb 2;14(1):555. doi: 10.1038/s41467-023-36269-7. Nat Commun. 2023. PMID: 36732331 Free PMC article.
Genetic mapping of microbial and host traits reveals production of immunomodulatory lipids by Akkermansia muciniphila in the murine gut.
Zhang Q, Linke V, Overmyer KA, Traeger LL, Kasahara K, Miller IJ, Manson DE, Polaske TJ, Kerby RL, Kemis JH, Trujillo EA, Reddy TR, Russell JD, Schueler KL, Stapleton DS, Rabaglia ME, Seldin M, Gatti DM, Keele GR, Pham DT, Gerdt JP, Vivas EI, Lusis AJ, Keller MP, Churchill GA, Blackwell HE, Broman KW, Attie AD, Coon JJ, Rey FE. Zhang Q, et al. Among authors: keele gr. Nat Microbiol. 2023 Mar;8(3):424-440. doi: 10.1038/s41564-023-01326-w. Epub 2023 Feb 9. Nat Microbiol. 2023. PMID: 36759753 Free PMC article.
37 results