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Spontaneous liver disease in wild-type C57BL/6JOlaHsd mice fed semisynthetic diet.
Ronda OAHO, van de Heijning BJM, de Bruin A, Thomas RE, Martini I, Koehorst M, Gerding A, Koster MH, Bloks VW, Jurdzinski A, Mulder NL, Havinga R, van der Beek EM, Reijngoud DJ, Kuipers F, Verkade HJ. Ronda OAHO, et al. Among authors: de bruin a. PLoS One. 2020 Sep 21;15(9):e0232069. doi: 10.1371/journal.pone.0232069. eCollection 2020. PLoS One. 2020. PMID: 32956351 Free PMC article.
Increased hepatic CD36 expression with age is associated with enhanced susceptibility to nonalcoholic fatty liver disease.
Sheedfar F, Sung MM, Aparicio-Vergara M, Kloosterhuis NJ, Miquilena-Colina ME, Vargas-Castrillón J, Febbraio M, Jacobs RL, de Bruin A, Vinciguerra M, García-Monzón C, Hofker MH, Dyck JR, Koonen DP. Sheedfar F, et al. Among authors: de bruin a. Aging (Albany NY). 2014 Apr;6(4):281-95. doi: 10.18632/aging.100652. Aging (Albany NY). 2014. PMID: 24751397 Free PMC article.
Chemokine-like receptor 1 deficiency does not affect the development of insulin resistance and nonalcoholic fatty liver disease in mice.
Gruben N, Aparicio Vergara M, Kloosterhuis NJ, van der Molen H, Stoelwinder S, Youssef S, de Bruin A, Delsing DJ, Kuivenhoven JA, van de Sluis B, Hofker MH, Koonen DP. Gruben N, et al. Among authors: de bruin a. PLoS One. 2014 Apr 29;9(4):e96345. doi: 10.1371/journal.pone.0096345. eCollection 2014. PLoS One. 2014. PMID: 24781986 Free PMC article.
Effective treatment of steatosis and steatohepatitis by fibroblast growth factor 1 in mouse models of nonalcoholic fatty liver disease.
Liu W, Struik D, Nies VJ, Jurdzinski A, Harkema L, de Bruin A, Verkade HJ, Downes M, Evans RM, van Zutphen T, Jonker JW. Liu W, et al. Among authors: de bruin a. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2288-93. doi: 10.1073/pnas.1525093113. Epub 2016 Feb 8. Proc Natl Acad Sci U S A. 2016. PMID: 26858440 Free PMC article.
Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb.
Matondo RB, Toussaint MJ, Govaert KM, van Vuuren LD, Nantasanti S, Nijkamp MW, Pandit SK, Tooten PC, Koster MH, Holleman K, Schot A, Gu G, Spee B, Roskams T, Rinkes IB, Schotanus B, Kranenburg O, de Bruin A. Matondo RB, et al. Among authors: de bruin a. Oncotarget. 2016 Aug 23;7(34):54662-54675. doi: 10.18632/oncotarget.9952. Oncotarget. 2016. PMID: 27323406 Free PMC article.
NF-κB p65 serine 467 phosphorylation sensitizes mice to weight gain and TNFα-or diet-induced inflammation.
Riedlinger T, Dommerholt MB, Wijshake T, Kruit JK, Huijkman N, Dekker D, Koster M, Kloosterhuis N, Koonen DPY, de Bruin A, Baker D, Hofker MH, van Deursen J, Jonker JW, Schmitz ML, van de Sluis B. Riedlinger T, et al. Among authors: de bruin a. Biochim Biophys Acta Mol Cell Res. 2017 Oct;1864(10):1785-1798. doi: 10.1016/j.bbamcr.2017.07.005. Epub 2017 Jul 16. Biochim Biophys Acta Mol Cell Res. 2017. PMID: 28723419 Free article.
Atypical E2Fs inhibit tumor angiogenesis.
Weijts BGMW, Westendorp B, Hien BT, Martínez-López LM, Zijp M, Thurlings I, Thomas RE, Schulte-Merker S, Bakker WJ, de Bruin A. Weijts BGMW, et al. Among authors: de bruin a. Oncogene. 2018 Jan 11;37(2):271-276. doi: 10.1038/onc.2017.336. Epub 2017 Sep 18. Oncogene. 2018. PMID: 28925392 Free PMC article.
A Proinflammatory Gut Microbiota Increases Systemic Inflammation and Accelerates Atherosclerosis.
Brandsma E, Kloosterhuis NJ, Koster M, Dekker DC, Gijbels MJJ, van der Velden S, Ríos-Morales M, van Faassen MJR, Loreti MG, de Bruin A, Fu J, Kuipers F, Bakker BM, Westerterp M, de Winther MPJ, Hofker MH, van de Sluis B, Koonen DPY. Brandsma E, et al. Among authors: de winther mpj, de bruin a. Circ Res. 2019 Jan 4;124(1):94-100. doi: 10.1161/CIRCRESAHA.118.313234. Circ Res. 2019. PMID: 30582442 Free PMC article.
LED-phototherapy does not induce oxidative DNA damage in hyperbilirubinemic Gunn rats.
van der Schoor LWE, Hulzebos CV, van Faassen MH, Kema IP, de Bruin A, Havinga R, Koster M, Youssef SA, Bongiovanni L, Jonker JW, Verkade HJ. van der Schoor LWE, et al. Among authors: de bruin a. Pediatr Res. 2019 Jun;85(7):1041-1047. doi: 10.1038/s41390-019-0367-y. Epub 2019 Mar 9. Pediatr Res. 2019. PMID: 30851724
381 results