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Oncolytic HSV Vectors and Anti-Tumor Immunity.
Glorioso JC, Cohen JB, Goins WF, Hall B, Jackson JW, Kohanbash G, Amankulor N, Kaur B, Caligiuri MA, Chiocca EA, Holland EC, Quéva C. Glorioso JC, et al. Among authors: caligiuri ma. Curr Issues Mol Biol. 2021;41:381-468. doi: 10.21775/cimb.041.381. Epub 2020 Sep 17. Curr Issues Mol Biol. 2021. PMID: 32938804 Free article. Review.
Cyclophosphamide enhances glioma virotherapy by inhibiting innate immune responses.
Fulci G, Breymann L, Gianni D, Kurozomi K, Rhee SS, Yu J, Kaur B, Louis DN, Weissleder R, Caligiuri MA, Chiocca EA. Fulci G, et al. Among authors: caligiuri ma. Proc Natl Acad Sci U S A. 2006 Aug 22;103(34):12873-8. doi: 10.1073/pnas.0605496103. Epub 2006 Aug 14. Proc Natl Acad Sci U S A. 2006. PMID: 16908838 Free PMC article.
Extracellular matrix protein CCN1 limits oncolytic efficacy in glioma.
Haseley A, Boone S, Wojton J, Yu L, Yoo JY, Yu J, Kurozumi K, Glorioso JC, Caligiuri MA, Kaur B. Haseley A, et al. Among authors: caligiuri ma. Cancer Res. 2012 Mar 15;72(6):1353-62. doi: 10.1158/0008-5472.CAN-11-2526. Epub 2012 Jan 26. Cancer Res. 2012. PMID: 22282654 Free PMC article.
The histone deacetylase inhibitor valproic acid lessens NK cell action against oncolytic virus-infected glioblastoma cells by inhibition of STAT5/T-BET signaling and generation of gamma interferon.
Alvarez-Breckenridge CA, Yu J, Price R, Wei M, Wang Y, Nowicki MO, Ha YP, Bergin S, Hwang C, Fernandez SA, Kaur B, Caligiuri MA, Chiocca EA. Alvarez-Breckenridge CA, et al. Among authors: caligiuri ma. J Virol. 2012 Apr;86(8):4566-77. doi: 10.1128/JVI.05545-11. Epub 2012 Feb 8. J Virol. 2012. PMID: 22318143 Free PMC article.
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Alvarez-Breckenridge CA, Yu J, Price R, Wojton J, Pradarelli J, Mao H, Wei M, Wang Y, He S, Hardcastle J, Fernandez SA, Kaur B, Lawler SE, Vivier E, Mandelboim O, Moretta A, Caligiuri MA, Chiocca EA. Alvarez-Breckenridge CA, et al. Among authors: caligiuri ma. Nat Med. 2012 Dec;18(12):1827-34. doi: 10.1038/nm.3013. Epub 2012 Nov 25. Nat Med. 2012. PMID: 23178246 Free PMC article.
Bortezomib-induced unfolded protein response increases oncolytic HSV-1 replication resulting in synergistic antitumor effects.
Yoo JY, Hurwitz BS, Bolyard C, Yu JG, Zhang J, Selvendiran K, Rath KS, He S, Bailey Z, Eaves D, Cripe TP, Parris DS, Caligiuri MA, Yu J, Old M, Kaur B. Yoo JY, et al. Among authors: caligiuri ma. Clin Cancer Res. 2014 Jul 15;20(14):3787-98. doi: 10.1158/1078-0432.CCR-14-0553. Epub 2014 May 9. Clin Cancer Res. 2014. PMID: 24815720 Free PMC article.
Use of miRNA response sequences to block off-target replication and increase the safety of an unattenuated, glioblastoma-targeted oncolytic HSV.
Mazzacurati L, Marzulli M, Reinhart B, Miyagawa Y, Uchida H, Goins WF, Li A, Kaur B, Caligiuri M, Cripe T, Chiocca EA, Amankulor N, Cohen JB, Glorioso JC, Grandi P. Mazzacurati L, et al. Mol Ther. 2015 Jan;23(1):99-107. doi: 10.1038/mt.2014.177. Epub 2014 Sep 9. Mol Ther. 2015. PMID: 25200130 Free PMC article.
482 results