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Page 1
Multi-omic studies on missense PLG variants in families with otitis media.
Bootpetch TC, Hafrén L, Elling CL, Baschal EE, Manichaikul AW, Pine HS, Szeremeta W, Scholes MA, Cass SP, Larson ED, Chan KH, Ishaq R, Prager JD, Shaikh RS, Gubbels SP, Yousaf A; University of Washington Center for Mendelian Genomics (UW-CMG); Wine TM, Bamshad MJ, Yoon PJ, Jenkins HA, Nickerson DA, Streubel SO, Friedman NR, Frank DN, Einarsdottir E, Kere J, Riazuddin S, Daly KA, Leal SM, Ryan AF, Mattila PS, Ahmed ZM, Sale MM, Chonmaitree T, Santos-Cortez RLP. Bootpetch TC, et al. Among authors: ryan af. Sci Rep. 2020 Sep 14;10(1):15035. doi: 10.1038/s41598-020-70498-w. Sci Rep. 2020. PMID: 32929111 Free PMC article.
Otitis media susceptibility and shifts in the head and neck microbiome due to SPINK5 variants.
Frank DN, Giese APJ, Hafren L, Bootpetch TC, Yarza TKL, Steritz MJ, Pedro M, Labra PJ, Daly KA, Tantoco MLC, Szeremeta W, Reyes-Quintos MRT, Ahankoob N, Llanes EGDV, Pine HS, Yousaf S, Ir D, Einarsdottir E, de la Cruz RAR, Lee NR, Nonato RMA, Robertson CE, Ong KMC, Magno JPM, Chiong ANE, Espiritu-Chiong MC, San Agustin ML, Cruz TLG, Abes GT, Bamshad MJ, Cutiongco-de la Paz EM, Kere J, Nickerson DA, Mohlke KL, Riazuddin S, Chan A, Mattila PS, Leal SM, Ryan AF, Ahmed ZM, Chonmaitree T, Sale MM, Chiong CM, Santos-Cortez RLP. Frank DN, et al. Among authors: ryan af. J Med Genet. 2021 Jul;58(7):442-452. doi: 10.1136/jmedgenet-2020-106844. Epub 2020 Jul 24. J Med Genet. 2021. PMID: 32709676 Free PMC article.
The role of CDHR3 in susceptibility to otitis media.
Hirsch SD, Elling CL, Bootpetch TC, Scholes MA, Hafrén L, Streubel SO, Pine HS, Wine TM, Szeremeta W, Prager JD, Einarsdottir E, Yousaf A, Baschal EE, Rehman S, Bamshad MJ, Nickerson DA, Riazuddin S, Leal SM, Ahmed ZM, Yoon PJ, Kere J, Chan KH, Mattila PS, Friedman NR, Chonmaitree T, Frank DN, Ryan AF, Santos-Cortez RLP. Hirsch SD, et al. Among authors: ryan af. J Mol Med (Berl). 2021 Nov;99(11):1571-1583. doi: 10.1007/s00109-021-02118-7. Epub 2021 Jul 28. J Mol Med (Berl). 2021. PMID: 34322716 Free PMC article.
The FUT2 Variant c.461G>A (p.Trp154*) Is Associated With Differentially Expressed Genes and Nasopharyngeal Microbiota Shifts in Patients With Otitis Media.
Elling CL, Scholes MA, Streubel SO, Larson ED, Wine TM, Bootpetch TC, Yoon PJ, Kofonow JM, Gubbels SP, Cass SP, Robertson CE, Jenkins HA, Prager JD, Frank DN, Chan KH, Friedman NR, Ryan AF, Santos-Cortez RLP. Elling CL, et al. Among authors: ryan af. Front Cell Infect Microbiol. 2022 Jan 14;11:798246. doi: 10.3389/fcimb.2021.798246. eCollection 2021. Front Cell Infect Microbiol. 2022. PMID: 35096646 Free PMC article.
FUT2 Variants Confer Susceptibility to Familial Otitis Media.
Santos-Cortez RLP, Chiong CM, Frank DN, Ryan AF, Giese APJ, Bootpetch Roberts T, Daly KA, Steritz MJ, Szeremeta W, Pedro M, Pine H, Yarza TKL, Scholes MA, Llanes EGDV, Yousaf S, Friedman N, Tantoco MLC, Wine TM, Labra PJ, Benoit J, Ruiz AG, de la Cruz RAR, Greenlee C, Yousaf A, Cardwell J, Nonato RMA, Ray D, Ong KMC, So E, Robertson CE, Dinwiddie J, Lagrana-Villagracia SM; University of Washington Center for Mendelian Genomics (UWCMG); Gubbels SP, Shaikh RS, Cass SP, Einarsdottir E, Lee NR, Schwartz DA, Gloria-Cruz TLI, Bamshad MJ, Yang IV, Kere J, Abes GT, Prager JD, Riazuddin S, Chan AL, Yoon PJ, Nickerson DA, Cutiongco-de la Paz EM, Streubel SO, Reyes-Quintos MRT, Jenkins HA, Mattila P, Chan KH, Mohlke KL, Leal SM, Hafrén L, Chonmaitree T, Sale MM, Ahmed ZM. Santos-Cortez RLP, et al. Among authors: ryan af. Am J Hum Genet. 2018 Nov 1;103(5):679-690. doi: 10.1016/j.ajhg.2018.09.010. Epub 2018 Oct 25. Am J Hum Genet. 2018. PMID: 30401457 Free PMC article.
Panel 3: Genomics, precision medicine and targeted therapies.
Santos-Cortez RLP, Bhutta MF, Earl JP, Hafrén L, Jennings M, Mell JC, Pichichero ME, Ryan AF, Tateossian H, Ehrlich GD. Santos-Cortez RLP, et al. Among authors: ryan af. Int J Pediatr Otorhinolaryngol. 2020 Mar;130 Suppl 1(Suppl 1):109835. doi: 10.1016/j.ijporl.2019.109835. Epub 2019 Dec 24. Int J Pediatr Otorhinolaryngol. 2020. PMID: 32007292 Free PMC article. Review.
Editorial: Otitis Media Genomics and the Middle Ear Microbiome.
Santos-Cortez RLP, Ehrlich GD, Ryan AF. Santos-Cortez RLP, et al. Among authors: ryan af. Front Genet. 2021 Oct 12;12:763688. doi: 10.3389/fgene.2021.763688. eCollection 2021. Front Genet. 2021. PMID: 34712274 Free PMC article. No abstract available.
Mouse models of induced otitis media.
Ryan AF, Ebmeyer J, Furukawa M, Pak K, Melhus A, Wasserman SI, Chung WH. Ryan AF, et al. Brain Res. 2006 May 26;1091(1):3-8. doi: 10.1016/j.brainres.2006.02.004. Epub 2006 Jun 9. Brain Res. 2006. PMID: 16764829 Review.
The role of DNA sensing and innate immune receptor TLR9 in otitis media.
Leichtle A, Hernandez M, Lee J, Pak K, Webster NJ, Wollenberg B, Wasserman SI, Ryan AF. Leichtle A, et al. Among authors: ryan af. Innate Immun. 2012 Feb;18(1):3-13. doi: 10.1177/1753425910393539. Epub 2011 Jan 14. Innate Immun. 2012. PMID: 21239460 Free PMC article.
295 results