Galietta LJV - Search Results

1

Current development of CFTR potentiators in the last decade.

Spanò V, Venturini A, Genovese M, Barreca M, Raimondi MV, Montalbano A, Galietta LJV, Barraja P. Spanò V, et al. Among authors: galietta ljv. Eur J Med Chem. 2020 Oct 15;204:112631. doi: 10.1016/j.ejmech.2020.112631. Epub 2020 Jul 15. Eur J Med Chem. 2020. PMID: 32898816 Review.

2

Synthesis of 4-thiophen-2'-yl-1,4-dihydropyridines as potentiators of the CFTR chloride channel.

Cateni F, Zacchigna M, Pedemonte N, Galietta LJ, Mazzei MT, Fossa P, Giampieri M, Mazzei M. Cateni F, et al. Bioorg Med Chem. 2009 Dec 1;17(23):7894-903. doi: 10.1016/j.bmc.2009.10.028. Epub 2009 Oct 20. Bioorg Med Chem. 2009. PMID: 19880323

3

Cystic fibrosis: a new target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines.

Budriesi R, Ioan P, Leoni A, Pedemonte N, Locatelli A, Micucci M, Chiarini A, Galietta LJ. Budriesi R, et al. J Med Chem. 2011 Jun 9;54(11):3885-94. doi: 10.1021/jm200199r. Epub 2011 May 13. J Med Chem. 2011. PMID: 21568323 Free PMC article.

4

The search for a common structural moiety among selected pharmacological correctors of the mutant CFTR chloride channel.

Nieddu E, Pollarolo B, Mazzei MT, Anzaldi M, Schenone S, Pedemonte N, Pesce E, Galietta LJ, Mazzei M. Nieddu E, et al. Future Med Chem. 2014;6(17):1857-68. doi: 10.4155/fmc.14.118. Future Med Chem. 2014. PMID: 25495980

5

Synthesis and structure-activity relationship of aminoarylthiazole derivatives as correctors of the chloride transport defect in cystic fibrosis.

Pesce E, Bellotti M, Liessi N, Guariento S, Damonte G, Cichero E, Galatini A, Salis A, Gianotti A, Pedemonte N, Zegarra-Moran O, Fossa P, Galietta LJ, Millo E. Pesce E, et al. Eur J Med Chem. 2015 Jun 24;99:14-35. doi: 10.1016/j.ejmech.2015.05.030. Epub 2015 May 28. Eur J Med Chem. 2015. PMID: 26041577

6

Novel Hits in the Correction of ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Protein: Synthesis, Pharmacological, and ADME Evaluation of Tetrahydropyrido[4,3-d]pyrimidines for the Potential Treatment of Cystic Fibrosis.

Pesci E, Bettinetti L, Fanti P, Galietta LJ, La Rosa S, Magnoni L, Pedemonte N, Sardone GL, Maccari L. Pesci E, et al. J Med Chem. 2015 Dec 24;58(24):9697-711. doi: 10.1021/acs.jmedchem.5b00771. Epub 2015 Dec 7. J Med Chem. 2015. PMID: 26561003

7

Evaluation of a systems biology approach to identify pharmacological correctors of the mutant CFTR chloride channel.

Pesce E, Gorrieri G, Sirci F, Napolitano F, Carrella D, Caci E, Tomati V, Zegarra-Moran O, di Bernardo D, Galietta LJ. Pesce E, et al. J Cyst Fibros. 2016 Jul;15(4):425-35. doi: 10.1016/j.jcf.2016.02.009. Epub 2016 Mar 10. J Cyst Fibros. 2016. PMID: 26971626 Free article.

8

Substituted 2-Acylaminocycloalkylthiophene-3-carboxylic Acid Arylamides as Inhibitors of the Calcium-Activated Chloride Channel Transmembrane Protein 16A (TMEM16A).

Truong EC, Phuan PW, Reggi AL, Ferrera L, Galietta LJV, Levy SE, Moises AC, Cil O, Diez-Cecilia E, Lee S, Verkman AS, Anderson MO. Truong EC, et al. Among authors: galietta ljv. J Med Chem. 2017 Jun 8;60(11):4626-4635. doi: 10.1021/acs.jmedchem.7b00020. Epub 2017 May 24. J Med Chem. 2017. PMID: 28493701 Free PMC article.

9

Bypassing CFTR dysfunction in cystic fibrosis with alternative pathways for anion transport.

Li H, Salomon JJ, Sheppard DN, Mall MA, Galietta LJ. Li H, et al. Curr Opin Pharmacol. 2017 Jun;34:91-97. doi: 10.1016/j.coph.2017.10.002. Epub 2017 Oct 21. Curr Opin Pharmacol. 2017. PMID: 29065356 Review.

10

High-throughput screening identifies FAU protein as a regulator of mutant cystic fibrosis transmembrane conductance regulator channel.

Tomati V, Pesce E, Caci E, Sondo E, Scudieri P, Marini M, Amato F, Castaldo G, Ravazzolo R, Galietta LJV, Pedemonte N. Tomati V, et al. Among authors: galietta ljv. J Biol Chem. 2018 Jan 26;293(4):1203-1217. doi: 10.1074/jbc.M117.816595. Epub 2017 Nov 20. J Biol Chem. 2018. PMID: 29158263 Free PMC article.

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