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Polygenic architecture informs potential vulnerability to drug-induced liver injury.
Koido M, Kawakami E, Fukumura J, Noguchi Y, Ohori M, Nio Y, Nicoletti P, Aithal GP, Daly AK, Watkins PB, Anayama H, Dragan Y, Shinozawa T, Takebe T. Koido M, et al. Among authors: takebe t. Nat Med. 2020 Oct;26(10):1541-1548. doi: 10.1038/s41591-020-1023-0. Epub 2020 Sep 7. Nat Med. 2020. PMID: 32895570 Free PMC article.
Multilineage communication regulates human liver bud development from pluripotency.
Camp JG, Sekine K, Gerber T, Loeffler-Wirth H, Binder H, Gac M, Kanton S, Kageyama J, Damm G, Seehofer D, Belicova L, Bickle M, Barsacchi R, Okuda R, Yoshizawa E, Kimura M, Ayabe H, Taniguchi H, Takebe T, Treutlein B. Camp JG, et al. Among authors: takebe t. Nature. 2017 Jun 22;546(7659):533-538. doi: 10.1038/nature22796. Epub 2017 Jun 14. Nature. 2017. PMID: 28614297
Massive and Reproducible Production of Liver Buds Entirely from Human Pluripotent Stem Cells.
Takebe T, Sekine K, Kimura M, Yoshizawa E, Ayano S, Koido M, Funayama S, Nakanishi N, Hisai T, Kobayashi T, Kasai T, Kitada R, Mori A, Ayabe H, Ejiri Y, Amimoto N, Yamazaki Y, Ogawa S, Ishikawa M, Kiyota Y, Sato Y, Nozawa K, Okamoto S, Ueno Y, Taniguchi H. Takebe T, et al. Cell Rep. 2017 Dec 5;21(10):2661-2670. doi: 10.1016/j.celrep.2017.11.005. Cell Rep. 2017. PMID: 29212014 Free article.
Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids.
Ouchi R, Togo S, Kimura M, Shinozawa T, Koido M, Koike H, Thompson W, Karns RA, Mayhew CN, McGrath PS, McCauley HA, Zhang RR, Lewis K, Hakozaki S, Ferguson A, Saiki N, Yoneyama Y, Takeuchi I, Mabuchi Y, Akazawa C, Yoshikawa HY, Wells JM, Takebe T. Ouchi R, et al. Among authors: takebe t. Cell Metab. 2019 Aug 6;30(2):374-384.e6. doi: 10.1016/j.cmet.2019.05.007. Epub 2019 May 30. Cell Metab. 2019. PMID: 31155493 Free PMC article.
Creativity for a cure.
Takebe T. Takebe T. Nat Med. 2019 Jun;25(6):868. doi: 10.1038/s41591-019-0471-x. Nat Med. 2019. PMID: 31171868 No abstract available.
High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell-Derived Organoids.
Shinozawa T, Kimura M, Cai Y, Saiki N, Yoneyama Y, Ouchi R, Koike H, Maezawa M, Zhang RR, Dunn A, Ferguson A, Togo S, Lewis K, Thompson WL, Asai A, Takebe T. Shinozawa T, et al. Among authors: takebe t. Gastroenterology. 2021 Feb;160(3):831-846.e10. doi: 10.1053/j.gastro.2020.10.002. Epub 2020 Oct 8. Gastroenterology. 2021. PMID: 33039464 Free PMC article.
157 results