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Polygenic architecture informs potential vulnerability to drug-induced liver injury.
Koido M, Kawakami E, Fukumura J, Noguchi Y, Ohori M, Nio Y, Nicoletti P, Aithal GP, Daly AK, Watkins PB, Anayama H, Dragan Y, Shinozawa T, Takebe T. Koido M, et al. Among authors: dragan y. Nat Med. 2020 Oct;26(10):1541-1548. doi: 10.1038/s41591-020-1023-0. Epub 2020 Sep 7. Nat Med. 2020. PMID: 32895570 Free PMC article.
Quantitative Systems Toxicology Analysis of In Vitro Mechanistic Assays Reveals Importance of Bile Acid Accumulation and Mitochondrial Dysfunction in TAK-875-Induced Liver Injury.
Longo DM, Woodhead JL, Walker P, Herédi-Szabó K, Mogyorósi K, Wolenski FS, Dragan YP, Mosedale M, Siler SQ, Watkins PB, Howell BA. Longo DM, et al. Among authors: dragan yp. Toxicol Sci. 2019 Feb 1;167(2):458-467. doi: 10.1093/toxsci/kfy253. Toxicol Sci. 2019. PMID: 30289550 Free PMC article.
Early prediction of polymyxin-induced nephrotoxicity with next-generation urinary kidney injury biomarkers.
Keirstead ND, Wagoner MP, Bentley P, Blais M, Brown C, Cheatham L, Ciaccio P, Dragan Y, Ferguson D, Fikes J, Galvin M, Gupta A, Hale M, Johnson N, Luo W, McGrath F, Pietras M, Price S, Sathe AG, Sasaki JC, Snow D, Walsky RL, Kern G. Keirstead ND, et al. Among authors: dragan y. Toxicol Sci. 2014 Feb;137(2):278-91. doi: 10.1093/toxsci/kft247. Epub 2013 Nov 4. Toxicol Sci. 2014. PMID: 24189134
Understanding drug-cytokine synergistic toxicity.
Wolenski FS, Dragan YP. Wolenski FS, et al. Among authors: dragan yp. Cell Death Dis. 2015 Nov 19;6(11):e1988. doi: 10.1038/cddis.2015.321. Cell Death Dis. 2015. PMID: 26583328 Free PMC article. No abstract available.
104 results