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A phase II trial of GSK2256098 and trametinib in patients with advanced pancreatic ductal adenocarcinoma.
Aung KL, McWhirter E, Welch S, Wang L, Lovell S, Stayner LA, Ali S, Malpage A, Makepeace B, Ramachandran M, Jang GH, Gallinger S, Zhang T, Stockley TL, Fischer SE, Dhani N, Hedley D, Knox JJ, Siu LL, Goodwin R, Bedard PL. Aung KL, et al. Among authors: jang gh. J Gastrointest Oncol. 2022 Dec;13(6):3216-3226. doi: 10.21037/jgo-22-86. J Gastrointest Oncol. 2022. PMID: 36636049 Free PMC article.
Whole-genome sequencing of 20 cholangiocarcinoma cases reveals unique profiles in patients with cirrhosis and primary sclerosing cholangitis.
Holzapfel N, Zhang A, Choi WJ, Denroche R, Jang G, Dodd A, Bucur R, Wilson J, Sapisochin G, Notta F, Grant RC, Gallinger S, Knox JJ, O'Kane GM. Holzapfel N, et al. J Gastrointest Oncol. 2023 Feb 28;14(1):379-389. doi: 10.21037/jgo-22-676. Epub 2023 Feb 3. J Gastrointest Oncol. 2023. PMID: 36915452 Free PMC article.
A Four-Chemokine Signature Is Associated with a T-cell-Inflamed Phenotype in Primary and Metastatic Pancreatic Cancer.
Romero JM, Grünwald B, Jang GH, Bavi PP, Jhaveri A, Masoomian M, Fischer SE, Zhang A, Denroche RE, Lungu IM, De Luca A, Bartlett JMS, Xu J, Li N, Dhaliwal S, Liang SB, Chadwick D, Vyas F, Bronsert P, Khokha R, McGaha TL, Notta F, Ohashi PS, Done SJ, O'Kane GM, Wilson JM, Knox JJ, Connor A, Wang Y, Zogopoulos G, Gallinger S. Romero JM, et al. Among authors: jang gh. Clin Cancer Res. 2020 Apr 15;26(8):1997-2010. doi: 10.1158/1078-0432.CCR-19-2803. Epub 2020 Jan 21. Clin Cancer Res. 2020. PMID: 31964786
Mitochondrial fitness and cancer risk.
Kossenkov AV, Milcarek A, Notta F, Jang GH, Wilson JM, Gallinger S, Zhou DC, Ding L, Ghosh JC, Perego M, Morotti A, Locatelli M, Robert ME, Vaira V, Altieri DC. Kossenkov AV, et al. Among authors: jang gh. PLoS One. 2022 Oct 12;17(10):e0273520. doi: 10.1371/journal.pone.0273520. eCollection 2022. PLoS One. 2022. PMID: 36223343 Free PMC article.
NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4.
Jain P, Dvorkin-Gheva A, Mollen E, Malbeteau L, Xie M, Jessa F, Dhavarasa P, Chung S, Brown KR, Jang GH, Vora P, Notta F, Moffat J, Hedley D, Boutros PC, Wouters BG, Koritzinsky M. Jain P, et al. Among authors: jang gh. Sci Adv. 2021 May 7;7(19):eabf7114. doi: 10.1126/sciadv.abf7114. Print 2021 May. Sci Adv. 2021. PMID: 33962950 Free PMC article.
Meta-Analysis of 1,200 Transcriptomic Profiles Identifies a Prognostic Model for Pancreatic Ductal Adenocarcinoma.
Sandhu V, Labori KJ, Borgida A, Lungu I, Bartlett J, Hafezi-Bakhtiari S, Denroche RE, Jang GH, Pasternack D, Mbaabali F, Watson M, Wilson J, Kure EH, Gallinger S, Haibe-Kains B. Sandhu V, et al. Among authors: jang gh. JCO Clin Cancer Inform. 2019 May;3:1-16. doi: 10.1200/CCI.18.00102. JCO Clin Cancer Inform. 2019. PMID: 31070984 Free article.
Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial.
Aung KL, Fischer SE, Denroche RE, Jang GH, Dodd A, Creighton S, Southwood B, Liang SB, Chadwick D, Zhang A, O'Kane GM, Albaba H, Moura S, Grant RC, Miller JK, Mbabaali F, Pasternack D, Lungu IM, Bartlett JMS, Ghai S, Lemire M, Holter S, Connor AA, Moffitt RA, Yeh JJ, Timms L, Krzyzanowski PM, Dhani N, Hedley D, Notta F, Wilson JM, Moore MJ, Gallinger S, Knox JJ. Aung KL, et al. Among authors: jang gh. Clin Cancer Res. 2018 Mar 15;24(6):1344-1354. doi: 10.1158/1078-0432.CCR-17-2994. Epub 2017 Dec 29. Clin Cancer Res. 2018. PMID: 29288237 Free PMC article.
Spatially confined sub-tumor microenvironments in pancreatic cancer.
Grünwald BT, Devisme A, Andrieux G, Vyas F, Aliar K, McCloskey CW, Macklin A, Jang GH, Denroche R, Romero JM, Bavi P, Bronsert P, Notta F, O'Kane G, Wilson J, Knox J, Tamblyn L, Udaskin M, Radulovich N, Fischer SE, Boerries M, Gallinger S, Kislinger T, Khokha R. Grünwald BT, et al. Among authors: jang gh. Cell. 2021 Oct 28;184(22):5577-5592.e18. doi: 10.1016/j.cell.2021.09.022. Epub 2021 Oct 12. Cell. 2021. PMID: 34644529 Free article.
138 results