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Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.
Asadi Shahmirzadi A, Edgar D, Liao CY, Hsu YM, Lucanic M, Asadi Shahmirzadi A, Wiley CD, Gan G, Kim DE, Kasler HG, Kuehnemann C, Kaplowitz B, Bhaumik D, Riley RR, Kennedy BK, Lithgow GJ. Asadi Shahmirzadi A, et al. Among authors: kennedy bk. Cell Metab. 2020 Sep 1;32(3):447-456.e6. doi: 10.1016/j.cmet.2020.08.004. Cell Metab. 2020. PMID: 32877690 Free PMC article.
Will the real aging Sirtuin please stand up?
Liao CY, Kennedy BK. Liao CY, et al. Among authors: kennedy bk. Cell Res. 2012 Aug;22(8):1215-7. doi: 10.1038/cr.2012.62. Epub 2012 Apr 17. Cell Res. 2012. PMID: 22508266 Free PMC article.
Late-life rapamycin treatment reverses age-related heart dysfunction.
Flynn JM, O'Leary MN, Zambataro CA, Academia EC, Presley MP, Garrett BJ, Zykovich A, Mooney SD, Strong R, Rosen CJ, Kapahi P, Nelson MD, Kennedy BK, Melov S. Flynn JM, et al. Among authors: kennedy bk. Aging Cell. 2013 Oct;12(5):851-62. doi: 10.1111/acel.12109. Epub 2013 Jul 7. Aging Cell. 2013. PMID: 23734717 Free PMC article.
Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population.
Levine ME, Suarez JA, Brandhorst S, Balasubramanian P, Cheng CW, Madia F, Fontana L, Mirisola MG, Guevara-Aguirre J, Wan J, Passarino G, Kennedy BK, Wei M, Cohen P, Crimmins EM, Longo VD. Levine ME, et al. Among authors: kennedy bk. Cell Metab. 2014 Mar 4;19(3):407-17. doi: 10.1016/j.cmet.2014.02.006. Cell Metab. 2014. PMID: 24606898 Free PMC article.
Mouse models and aging: longevity and progeria.
Liao CY, Kennedy BK. Liao CY, et al. Among authors: kennedy bk. Curr Top Dev Biol. 2014;109:249-85. doi: 10.1016/B978-0-12-397920-9.00003-2. Curr Top Dev Biol. 2014. PMID: 24947239 Review.
Geroscience: linking aging to chronic disease.
Kennedy BK, Berger SL, Brunet A, Campisi J, Cuervo AM, Epel ES, Franceschi C, Lithgow GJ, Morimoto RI, Pessin JE, Rando TA, Richardson A, Schadt EE, Wyss-Coray T, Sierra F. Kennedy BK, et al. Cell. 2014 Nov 6;159(4):709-13. doi: 10.1016/j.cell.2014.10.039. Cell. 2014. PMID: 25417146 Free PMC article.
Interventions to Slow Aging in Humans: Are We Ready?
Longo VD, Antebi A, Bartke A, Barzilai N, Brown-Borg HM, Caruso C, Curiel TJ, de Cabo R, Franceschi C, Gems D, Ingram DK, Johnson TE, Kennedy BK, Kenyon C, Klein S, Kopchick JJ, Lepperdinger G, Madeo F, Mirisola MG, Mitchell JR, Passarino G, Rudolph KL, Sedivy JM, Shadel GS, Sinclair DA, Spindler SR, Suh Y, Vijg J, Vinciguerra M, Fontana L. Longo VD, et al. Among authors: kennedy bk. Aging Cell. 2015 Aug;14(4):497-510. doi: 10.1111/acel.12338. Epub 2015 Apr 22. Aging Cell. 2015. PMID: 25902704 Free PMC article. Review.
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.
Brandhorst S, Choi IY, Wei M, Cheng CW, Sedrakyan S, Navarrete G, Dubeau L, Yap LP, Park R, Vinciguerra M, Di Biase S, Mirzaei H, Mirisola MG, Childress P, Ji L, Groshen S, Penna F, Odetti P, Perin L, Conti PS, Ikeno Y, Kennedy BK, Cohen P, Morgan TE, Dorff TB, Longo VD. Brandhorst S, et al. Among authors: kennedy bk. Cell Metab. 2015 Jul 7;22(1):86-99. doi: 10.1016/j.cmet.2015.05.012. Epub 2015 Jun 18. Cell Metab. 2015. PMID: 26094889 Free PMC article. Clinical Trial.
239 results