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A gene therapy for inherited blindness using dCas9-VPR-mediated transcriptional activation.
Böhm S, Splith V, Riedmayr LM, Rötzer RD, Gasparoni G, Nordström KJV, Wagner JE, Hinrichsmeyer KS, Walter J, Wahl-Schott C, Fenske S, Biel M, Michalakis S, Becirovic E. Böhm S, et al. Among authors: nordstrom kjv. Sci Adv. 2020 Aug 19;6(34):eaba5614. doi: 10.1126/sciadv.aba5614. eCollection 2020 Aug. Sci Adv. 2020. PMID: 32875106 Free PMC article.
Combining transcription factor binding affinities with open-chromatin data for accurate gene expression prediction.
Schmidt F, Gasparoni N, Gasparoni G, Gianmoena K, Cadenas C, Polansky JK, Ebert P, Nordström K, Barann M, Sinha A, Fröhler S, Xiong J, Dehghani Amirabad A, Behjati Ardakani F, Hutter B, Zipprich G, Felder B, Eils J, Brors B, Chen W, Hengstler JG, Hamann A, Lengauer T, Rosenstiel P, Walter J, Schulz MH. Schmidt F, et al. Nucleic Acids Res. 2017 Jan 9;45(1):54-66. doi: 10.1093/nar/gkw1061. Epub 2016 Nov 29. Nucleic Acids Res. 2017. PMID: 27899623 Free PMC article.
Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control.
Brosch M, Kattler K, Herrmann A, von Schönfels W, Nordström K, Seehofer D, Damm G, Becker T, Zeissig S, Nehring S, Reichel F, Moser V, Thangapandi RV, Stickel F, Baretton G, Röcken C, Muders M, Matz-Soja M, Krawczak M, Gasparoni G, Hartmann H, Dahl A, Schafmayer C, Walter J, Hampe J. Brosch M, et al. Nat Commun. 2018 Oct 8;9(1):4150. doi: 10.1038/s41467-018-06611-5. Nat Commun. 2018. PMID: 30297808 Free PMC article.
Integrative analysis of single-cell expression data reveals distinct regulatory states in bidirectional promoters.
Behjati Ardakani F, Kattler K, Nordström K, Gasparoni N, Gasparoni G, Fuchs S, Sinha A, Barann M, Ebert P, Fischer J, Hutter B, Zipprich G, Imbusch CD, Felder B, Eils J, Brors B, Lengauer T, Manke T, Rosenstiel P, Walter J, Schulz MH. Behjati Ardakani F, et al. Epigenetics Chromatin. 2018 Nov 10;11(1):66. doi: 10.1186/s13072-018-0236-7. Epigenetics Chromatin. 2018. PMID: 30414612 Free PMC article.
Sodium chloride is an ionic checkpoint for human TH2 cells and shapes the atopic skin microenvironment.
Matthias J, Maul J, Noster R, Meinl H, Chao YY, Gerstenberg H, Jeschke F, Gasparoni G, Welle A, Walter J, Nordström K, Eberhardt K, Renisch D, Donakonda S, Knolle P, Soll D, Grabbe S, Garzorz-Stark N, Eyerich K, Biedermann T, Baumjohann D, Zielinski CE. Matthias J, et al. Sci Transl Med. 2019 Feb 20;11(480):eaau0683. doi: 10.1126/scitranslmed.aau0683. Sci Transl Med. 2019. PMID: 30787167
Unique and assay specific features of NOMe-, ATAC- and DNase I-seq data.
Nordström KJV, Schmidt F, Gasparoni N, Salhab A, Gasparoni G, Kattler K, Müller F, Ebert P, Costa IG; DEEP consortium; Pfeifer N, Lengauer T, Schulz MH, Walter J. Nordström KJV, et al. Nucleic Acids Res. 2019 Nov 18;47(20):10580-10596. doi: 10.1093/nar/gkz799. Nucleic Acids Res. 2019. PMID: 31584093 Free PMC article.
56 results