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Unleashing the therapeutic potential of apoptotic bodies.
Phan TK, Ozkocak DC, Poon IKH. Phan TK, et al. Among authors: poon ikh. Biochem Soc Trans. 2020 Oct 30;48(5):2079-2088. doi: 10.1042/BST20200225. Biochem Soc Trans. 2020. PMID: 32869835 Free PMC article. Review.
Phenotypic screen for oxygen consumption rate identifies an anti-cancer naphthoquinone that induces mitochondrial oxidative stress.
Byrne FL, Olzomer EM, Marriott GR, Quek LE, Katen A, Su J, Nelson ME, Hart-Smith G, Larance M, Sebesfi VF, Cuff J, Martyn GE, Childress E, Alexopoulos SJ, Poon IK, Faux MC, Burgess AW, Reid G, McCarroll JA, Santos WL, Quinlan KG, Turner N, Fazakerley DJ, Kumar N, Hoehn KL. Byrne FL, et al. Redox Biol. 2020 Jan;28:101374. doi: 10.1016/j.redox.2019.101374. Epub 2019 Nov 5. Redox Biol. 2020. PMID: 31743887 Free PMC article.
Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane.
Kenwood BM, Weaver JL, Bajwa A, Poon IK, Byrne FL, Murrow BA, Calderone JA, Huang L, Divakaruni AS, Tomsig JL, Okabe K, Lo RH, Cameron Coleman G, Columbus L, Yan Z, Saucerman JJ, Smith JS, Holmes JW, Lynch KR, Ravichandran KS, Uchiyama S, Santos WL, Rogers GW, Okusa MD, Bayliss DA, Hoehn KL. Kenwood BM, et al. Mol Metab. 2013 Nov 28;3(2):114-23. doi: 10.1016/j.molmet.2013.11.005. eCollection 2014 Apr. Mol Metab. 2013. PMID: 24634817 Free PMC article.
The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity.
Santavanond JP, Chiu YH, Tixeira R, Liu Z, Yap JKY, Chen KW, Li CL, Lu YR, Roncero-Carol J, Hoijman E, Rutter SF, Shi B, Ryan GF, Hodge AL, Caruso S, Baxter AA, Ozkocak DC, Johnson C, Day ZI, Mayfosh AJ, Hulett MD, Phan TK, Atkin-Smith GK, Poon IKH. Santavanond JP, et al. Among authors: poon ikh. Cell Death Dis. 2024 Feb 9;15(2):123. doi: 10.1038/s41419-024-06513-z. Cell Death Dis. 2024. PMID: 38336804 Free PMC article.
Targeting Efferocytosis in Inflammaging.
Poon IKH, Ravichandran KS. Poon IKH, et al. Annu Rev Pharmacol Toxicol. 2024 Jan 23;64:339-357. doi: 10.1146/annurev-pharmtox-032723-110507. Epub 2023 Aug 16. Annu Rev Pharmacol Toxicol. 2024. PMID: 37585658 Free article. Review.
77 results