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Elucidation of remdesivir cytotoxicity pathways through genome-wide CRISPR-Cas9 screening and transcriptomics.
Akinci E, Cha M, Lin L, Yeo G, Hamilton MC, Donahue CJ, Bermudez-Cabrera HC, Zanetti LC, Chen M, Barkal SA, Khowpinitchai B, Chu N, Velimirovic M, Jodhani R, Fife JD, Sovrovic M, Cole PA, Davey RA, Cassa CA, Sherwood RI. Akinci E, et al. Among authors: cole pa. bioRxiv [Preprint]. 2020 Aug 28:2020.08.27.270819. doi: 10.1101/2020.08.27.270819. bioRxiv. 2020. PMID: 32869031 Free PMC article. Preprint.
Structural Requirements for Activity of Mind bomb1 in Notch Signaling.
Cao R, Gozlan O, Tveriakhina L, Zhou H, Jiang H, Cole PA, Aster JC, Sprinzak D, Blacklow SC. Cao R, et al. Among authors: cole pa. bioRxiv [Preprint]. 2024 Mar 3:2024.03.01.582834. doi: 10.1101/2024.03.01.582834. bioRxiv. 2024. PMID: 38464278 Free PMC article. Preprint.
Asymmetric Engagement of Dimeric CRL3 KBTBD4 by the Molecular Glue UM171 Licenses Degradation of HDAC1/2 Complexes.
Yeo MJ, Zhang O, Xie X, Nam E, Payne NC, Gosavi PM, Kwok HS, Iram I, Lee C, Li J, Chen NJ, Jiang H, Wang ZA, Lee K, Mao H, Harry SA, Barakat IA, Takahashi M, Waterbury AL, Barone M, Mattevi A, Bar-Peled L, Cole PA, Mazitschek R, Liau BB, Zheng N. Yeo MJ, et al. Among authors: cole pa. bioRxiv [Preprint]. 2024 May 14:2024.05.14.593897. doi: 10.1101/2024.05.14.593897. bioRxiv. 2024. PMID: 38798619 Free PMC article. Preprint.
KBTBD4 Cancer Hotspot Mutations Drive Neomorphic Degradation of HDAC1/2 Corepressor Complexes.
Xie X, Zhang O, Yeo MJR, Lee C, Harry SA, Paul L, Li Y, Payne NC, Nam E, Kwok HS, Jiang H, Mao H, Hadley JL, Lin H, Batts M, Gosavi PM, D'Angiolella V, Cole PA, Mazitschek R, Northcott PA, Zheng N, Liau BB. Xie X, et al. Among authors: cole pa. bioRxiv [Preprint]. 2024 May 14:2024.05.14.593970. doi: 10.1101/2024.05.14.593970. bioRxiv. 2024. PMID: 38798357 Free PMC article. Preprint.
Does Transparency of Ankle Implant Costs Influence Surgeon Behavior?
Swenson R, Paull T, Moua G, Weatherby D, Azzam K, Wojahn R, Anderson S, Cole PA, Nguyen M. Swenson R, et al. Among authors: cole pa. Foot Ankle Orthop. 2024 Apr 23;9(2):24730114241247826. doi: 10.1177/24730114241247826. eCollection 2024 Apr. Foot Ankle Orthop. 2024. PMID: 38659719 Free PMC article.
p300 KAT regulates SOX10 stability and function in human melanoma.
Waddell A, Grbic N, Leibowitz K, Wyant WA, Choudhury S, Park K, Collard M, Cole PA, Alani RM. Waddell A, et al. Among authors: cole pa. bioRxiv [Preprint]. 2024 Feb 23:2024.02.20.581224. doi: 10.1101/2024.02.20.581224. bioRxiv. 2024. PMID: 38469149 Free PMC article. Preprint.
NEDD4L intramolecular interactions regulate its auto and substrate NaV1.5 ubiquitination.
Wright KM, Nathan S, Jiang H, Xia W, Kim H, Chakouri N, Nwafor JN, Fossier L, Srinivasan L, Chen Z, Boronina T, Post J, Paul S, Cole RN, Ben-Johny M, Cole PA, Gabelli SB. Wright KM, et al. Among authors: cole pa. J Biol Chem. 2024 Mar;300(3):105715. doi: 10.1016/j.jbc.2024.105715. Epub 2024 Feb 2. J Biol Chem. 2024. PMID: 38309503 Free PMC article.
The C-Terminal of NaV1.7 Is Ubiquitinated by NEDD4L.
Wright KM, Jiang H, Xia W, Murphy MB, Boronina TN, Nwafor JN, Kim H, Iheanacho AM, Azurmendi PA, Cole RN, Cole PA, Gabelli SB. Wright KM, et al. Among authors: cole pa. ACS Bio Med Chem Au. 2023 Oct 13;3(6):516-527. doi: 10.1021/acsbiomedchemau.3c00031. eCollection 2023 Dec 20. ACS Bio Med Chem Au. 2023. PMID: 38144259 Free PMC article.
472 results