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The SNM1A DNA repair nuclease.
Baddock HT, Yosaatmadja Y, Newman JA, Schofield CJ, Gileadi O, McHugh PJ. Baddock HT, et al. Among authors: schofield cj. DNA Repair (Amst). 2020 Nov;95:102941. doi: 10.1016/j.dnarep.2020.102941. Epub 2020 Jul 31. DNA Repair (Amst). 2020. PMID: 32866775 Free PMC article. Review.
Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Ng SS, Kavanagh KL, McDonough MA, Butler D, Pilka ES, Lienard BM, Bray JE, Savitsky P, Gileadi O, von Delft F, Rose NR, Offer J, Scheinost JC, Borowski T, Sundstrom M, Schofield CJ, Oppermann U. Ng SS, et al. Among authors: schofield cj. Nature. 2007 Jul 5;448(7149):87-91. doi: 10.1038/nature05971. Epub 2007 Jun 24. Nature. 2007. PMID: 17589501
Human SNM1A suppresses the DNA repair defects of yeast pso2 mutants.
Hazrati A, Ramis-Castelltort M, Sarkar S, Barber LJ, Schofield CJ, Hartley JA, McHugh PJ. Hazrati A, et al. Among authors: schofield cj. DNA Repair (Amst). 2008 Feb 1;7(2):230-8. doi: 10.1016/j.dnarep.2007.09.013. Epub 2007 Nov 19. DNA Repair (Amst). 2008. PMID: 18006388
Human SNM1A and XPF-ERCC1 collaborate to initiate DNA interstrand cross-link repair.
Wang AT, Sengerová B, Cattell E, Inagawa T, Hartley JM, Kiakos K, Burgess-Brown NA, Swift LP, Enzlin JH, Schofield CJ, Gileadi O, Hartley JA, McHugh PJ. Wang AT, et al. Among authors: schofield cj. Genes Dev. 2011 Sep 1;25(17):1859-70. doi: 10.1101/gad.15699211. Genes Dev. 2011. PMID: 21896658 Free PMC article.
Characterization of the human SNM1A and SNM1B/Apollo DNA repair exonucleases.
Sengerová B, Allerston CK, Abu M, Lee SY, Hartley J, Kiakos K, Schofield CJ, Hartley JA, Gileadi O, McHugh PJ. Sengerová B, et al. Among authors: schofield cj. J Biol Chem. 2012 Jul 27;287(31):26254-67. doi: 10.1074/jbc.M112.367243. Epub 2012 Jun 11. J Biol Chem. 2012. PMID: 22692201 Free PMC article.
Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers.
Brem J, van Berkel SS, Zollman D, Lee SY, Gileadi O, McHugh PJ, Walsh TR, McDonough MA, Schofield CJ. Brem J, et al. Among authors: schofield cj. Antimicrob Agents Chemother. 2015 Oct 19;60(1):142-50. doi: 10.1128/AAC.01335-15. Print 2016 Jan. Antimicrob Agents Chemother. 2015. PMID: 26482303 Free PMC article.
The Chemical Biology of Human Metallo-β-Lactamase Fold Proteins.
Pettinati I, Brem J, Lee SY, McHugh PJ, Schofield CJ. Pettinati I, et al. Among authors: schofield cj. Trends Biochem Sci. 2016 Apr;41(4):338-355. doi: 10.1016/j.tibs.2015.12.007. Epub 2016 Jan 21. Trends Biochem Sci. 2016. PMID: 26805042 Free PMC article. Review.
In Silico Fragment-Based Design Identifies Subfamily B1 Metallo-β-lactamase Inhibitors.
Cain R, Brem J, Zollman D, McDonough MA, Johnson RM, Spencer J, Makena A, Abboud MI, Cahill S, Lee SY, McHugh PJ, Schofield CJ, Fishwick CWG. Cain R, et al. Among authors: schofield cj. J Med Chem. 2018 Feb 8;61(3):1255-1260. doi: 10.1021/acs.jmedchem.7b01728. Epub 2018 Jan 10. J Med Chem. 2018. PMID: 29271657 Free article.
710 results