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Murine induced pluripotent stem cell-derived neuroimmune cell culture models emphasize opposite immune-effector functions of interleukin 13-primed microglia and macrophages in terms of neuroimmune toxicity.
Quarta A, Meese T, Pieters Z, Van Breedam E, Le Blon D, Van Broeckhoven J, Hendrix S, Goossens H, Hens N, Berneman Z, Van Nieuwerburgh F, Ponsaerts P. Quarta A, et al. Among authors: hendrix s. Glia. 2021 Feb;69(2):326-345. doi: 10.1002/glia.23899. Epub 2020 Aug 31. Glia. 2021. PMID: 32865285
In Vivo Interleukin-13-Primed Macrophages Contribute to Reduced Alloantigen-Specific T Cell Activation and Prolong Immunological Survival of Allogeneic Mesenchymal Stem Cell Implants.
Hoornaert CJ, Luyckx E, Reekmans K, Dhainaut M, Guglielmetti C, Le Blon D, Dooley D, Fransen E, Daans J, Verbeeck L, Quarta A, De Vocht N, Lemmens E, Goossens H, Van der Linden A, Roobrouck VD, Verfaillie C, Hendrix S, Moser M, Berneman ZN, Ponsaerts P. Hoornaert CJ, et al. Among authors: hendrix s. Stem Cells. 2016 Jul;34(7):1971-84. doi: 10.1002/stem.2360. Epub 2016 Mar 28. Stem Cells. 2016. PMID: 26992046
Interleukin-13 immune gene therapy prevents CNS inflammation and demyelination via alternative activation of microglia and macrophages.
Guglielmetti C, Le Blon D, Santermans E, Salas-Perdomo A, Daans J, De Vocht N, Shah D, Hoornaert C, Praet J, Peerlings J, Kara F, Bigot C, Mai Z, Goossens H, Hens N, Hendrix S, Verhoye M, Planas AM, Berneman Z, van der Linden A, Ponsaerts P. Guglielmetti C, et al. Among authors: hendrix s. Glia. 2016 Dec;64(12):2181-2200. doi: 10.1002/glia.23053. Epub 2016 Sep 29. Glia. 2016. PMID: 27685637
Intracerebral transplantation of interleukin 13-producing mesenchymal stem cells limits microgliosis, oligodendrocyte loss and demyelination in the cuprizone mouse model.
Le Blon D, Guglielmetti C, Hoornaert C, Quarta A, Daans J, Dooley D, Lemmens E, Praet J, De Vocht N, Reekmans K, Santermans E, Hens N, Goossens H, Verhoye M, Van der Linden A, Berneman Z, Hendrix S, Ponsaerts P. Le Blon D, et al. Among authors: hendrix s. J Neuroinflammation. 2016 Nov 9;13(1):288. doi: 10.1186/s12974-016-0756-7. J Neuroinflammation. 2016. PMID: 27829467 Free PMC article.
ADAM17-deficiency on microglia but not on macrophages promotes phagocytosis and functional recovery after spinal cord injury.
Sommer D, Corstjens I, Sanchez S, Dooley D, Lemmens S, Van Broeckhoven J, Bogie J, Vanmierlo T, Vidal PM, Rose-John S, Gou-Fabregas M, Hendrix S. Sommer D, et al. Among authors: hendrix s. Brain Behav Immun. 2019 Aug;80:129-145. doi: 10.1016/j.bbi.2019.02.032. Epub 2019 Mar 6. Brain Behav Immun. 2019. PMID: 30851378 Free article.
CD36-mediated uptake of myelin debris by macrophages and microglia reduces neuroinflammation.
Grajchen E, Wouters E, van de Haterd B, Haidar M, Hardonnière K, Dierckx T, Van Broeckhoven J, Erens C, Hendrix S, Kerdine-Römer S, Hendriks JJA, Bogie JFJ. Grajchen E, et al. Among authors: hendrix s. J Neuroinflammation. 2020 Jul 27;17(1):224. doi: 10.1186/s12974-020-01899-x. J Neuroinflammation. 2020. PMID: 32718316 Free PMC article.
372 results