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Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition.
St Amour CV, Sansó M, Bösken CA, Lee KM, Larochelle S, Zhang C, Shokat KM, Geyer M, Fisher RP. St Amour CV, et al. Among authors: fisher rp. Mol Cell Biol. 2012 Jul;32(13):2372-83. doi: 10.1128/MCB.06657-11. Epub 2012 Apr 16. Mol Cell Biol. 2012. PMID: 22508988 Free PMC article.
A positive feedback loop links opposing functions of P-TEFb/Cdk9 and histone H2B ubiquitylation to regulate transcript elongation in fission yeast.
Sansó M, Lee KM, Viladevall L, Jacques PÉ, Pagé V, Nagy S, Racine A, St Amour CV, Zhang C, Shokat KM, Schwer B, Robert F, Fisher RP, Tanny JC. Sansó M, et al. Among authors: fisher rp. PLoS Genet. 2012;8(8):e1002822. doi: 10.1371/journal.pgen.1002822. Epub 2012 Aug 2. PLoS Genet. 2012. PMID: 22876190 Free PMC article.
Pause, play, repeat: CDKs push RNAP II's buttons.
Sansó M, Fisher RP. Sansó M, et al. Among authors: fisher rp. Transcription. 2013 Jul-Aug;4(4):146-52. doi: 10.4161/trns.25146. Epub 2013 Jun 11. Transcription. 2013. PMID: 23756342 Free PMC article. Review.
The structure and substrate specificity of human Cdk12/Cyclin K.
Bösken CA, Farnung L, Hintermair C, Merzel Schachter M, Vogel-Bachmayr K, Blazek D, Anand K, Fisher RP, Eick D, Geyer M. Bösken CA, et al. Among authors: fisher rp. Nat Commun. 2014 Mar 24;5:3505. doi: 10.1038/ncomms4505. Nat Commun. 2014. PMID: 24662513 Free PMC article.
162 results