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Save Your Maximum Tolerated Dose: How to Diagnose Procedure-Related Spinal Cord Lesions After Lumbar Intrathecal Bolus Administration of Oligonucleotides in Cynomolgus Monkeys.
Korte S, Luft J, von Keutz A, Runge F, Mecklenburg L, Wozniak MM, Zander S, Ludwig FT, Pajaziti B, Romeike A, Korytko P. Korte S, et al. Among authors: romeike a. Int J Toxicol. 2020 Nov/Dec;39(6):510-517. doi: 10.1177/1091581820951098. Epub 2020 Aug 28. Int J Toxicol. 2020. PMID: 32856507
Scientific and Regulatory Policy Committee Best Practices: Recommended ("Best") Practices for Informed (Non-blinded) Versus Masked (Blinded) Microscopic Evaluation in Animal Toxicity Studies.
Bolon B, Francke S, Caverly Rae JM, Polack E, Regan KS, McInnes EF, Young JK, Keane K, Perry R, Romeike A, Colman K, Jensen K, Nakano-Ito K, Galbreath EJ. Bolon B, et al. Among authors: romeike a. Toxicol Pathol. 2022 Dec;50(8):930-941. doi: 10.1177/01926233221135563. Epub 2022 Nov 14. Toxicol Pathol. 2022. PMID: 36377245
Research Relevant Conditions and Pathology in Nonhuman Primates.
Saravanan C, Flandre T, Hodo CL, Lewis AD, Mecklenburg L, Romeike A, Turner OC, Yen HY. Saravanan C, et al. Among authors: romeike a. ILAR J. 2020 Dec 31;61(2-3):139-166. doi: 10.1093/ilar/ilab017. ILAR J. 2020. PMID: 34129672 Free PMC article. Review.
Toxicologic Pathology Forum: Opinion on Interpretive Challenges for Procedure-Related Effects Associated With Direct Central Nervous System Delivery of Oligonucleotides to Rodents, Dogs, and Nonhuman Primates.
Berman-Booty LD, Klein SK, Mazur C, Schroeder J, Korte S, Ludwig FT, Romeike A, Bolon B, Grieves JL. Berman-Booty LD, et al. Among authors: romeike a. Toxicol Pathol. 2023 Aug;51(6):375-389. doi: 10.1177/01926233231218953. Epub 2024 Jan 5. Toxicol Pathol. 2023. PMID: 38179962
A new genotype of hepatitis A virus causing transient liver enzyme elevations in Mauritius-origin laboratory-housed Macaca fascicularis.
Mecklenburg L, Ducore R, Boyle M, Newell A, Boone L, Luft J, Romeike A, Haverkamp AK, Mansfield K, Penraat KA, Baczenas JJ, Minor N, O'Connor SL, O'Connor DH. Mecklenburg L, et al. Among authors: romeike a. Vet Pathol. 2024 May;61(3):488-496. doi: 10.1177/03009858231209691. Epub 2023 Nov 12. Vet Pathol. 2024. PMID: 37953600
The Influence of Geographical Origin, Age, Sex, and Animal Husbandry on the Spontaneous Histopathology of Laboratory Cynomolgus Macaques (Macaca Fascicularis): A Contemporary Global and Multisite Review of Historical Control Data.
Chamanza R, Naylor SW, Gregori M, Boyle M, Pereira Bacares ME, Drevon-Gaillot E, Romeike A, Courtney C, Johnson K, Turner J, Swierzawski N, Sharma AK. Chamanza R, et al. Among authors: romeike a. Toxicol Pathol. 2022 Jul;50(5):607-627. doi: 10.1177/01926233221096424. Epub 2022 May 10. Toxicol Pathol. 2022. PMID: 35535738
Characterizing Adversity of Lysosomal Accumulation in Nonclinical Toxicity Studies: Results from the 5th ESTP International Expert Workshop.
Lenz B, Braendli-Baiocco A, Engelhardt J, Fant P, Fischer H, Francke S, Fukuda R, Gröters S, Harada T, Harleman H, Kaufmann W, Kustermann S, Nolte T, Palazzi X, Pohlmeyer-Esch G, Popp A, Romeike A, Schulte A, Lima BS, Tomlinson L, Willard J, Wood CE, Yoshida M. Lenz B, et al. Among authors: romeike a. Toxicol Pathol. 2018 Feb;46(2):224-246. doi: 10.1177/0192623317749452. Toxicol Pathol. 2018. PMID: 29471779
Scientific and Regulatory Policy Committee Points to Consider: Histopathologic Evaluation in Safety Assessment Studies for PEGylated Pharmaceutical Products.
Irizarry Rovira AR, Bennet BM, Bolon B, Braendli-Baiocco A, Chandra S, Fleurance R, Garman R, Hutto D, Lane J, Romeike A, Sargeant A, Zimmerman B. Irizarry Rovira AR, et al. Among authors: romeike a. Toxicol Pathol. 2018 Aug;46(6):616-635. doi: 10.1177/0192623318791801. Epub 2018 Aug 9. Toxicol Pathol. 2018. PMID: 30092727 Review.
27 results